7B3H
Notum complex with ARUK3003909
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Palmitoleoyl-protein carboxylesterase NOTUM | polymer | 383 | 43567.1 | 1 | UniProt (Q6P988) Pfam (PF03283) In PDB | Homo sapiens (Human) | hNOTUM |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | A | 6-((3-(trifluoromethoxy)phenyl)thio)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one | non-polymer | 328.3 | 1 | Chemie (SSW) | |||
| 5 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A: 81 - 451 (UniProt: Q6P988)
| PDB | External Database | Details |
|---|---|---|
| Glu 78 | - | cloning artifact |
| Thr 79 | - | cloning artifact |
| Gly 80 | - | cloning artifact |
| Ser 330 | Cys 330 | engineered mutation |
| Gly 452 | - | expression tag |
| Thr 453 | - | expression tag |
| Lys 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43567.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1169.0 | |
| All* | Total formula weight | 44736.1 |
