7B3D

Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with AMP at position -4 (structure 3)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SARS-CoV-2 RNA-dependent RNA polymerase nsp12	polymer	935	107053.2	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
2	B (B)	SARS-CoV-2 nsp8	polymer	201	22175.3	1	UniProt (P0DTD1) Pfam (PF08717)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
3	C (C)	SARS-CoV-2 nsp7	polymer	86	9521.1	1	UniProt (P0DTD1) Pfam (PF08716)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
4	D (P)	RNA (5'-R(P*CP*UP*AP*CP*GP*CP*AP*GP*UP*G)-3')	polymer	15	4807.9	1		Severe acute respiratory syndrome coronavirus 2
5	E (T)	RNA (5'-R(P*UP*GP*CP*AP*CP*UP*GP*CP*GP*UP*AP*G)-3')	polymer	57	18138.7	1		Severe acute respiratory syndrome coronavirus 2
6	F, G (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A: 1 - 932 (UniProt: P0DTD1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

B: 1 - 198 (UniProt: P0DTD1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

C: 1 - 83 (UniProt: P0DTD1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	161696.2
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	161827.0

*Water molecules are not included.