7B30
MST3 in complex with compound G-5555
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase 24 | polymer | 306 | 34559.6 | 1 | UniProt (Q9Y6E0) Pfam (PF00069) | Homo sapiens (Human) | Mammalian STE20-like protein kinase 3,MST-3,STE20-like kinase MST3 |
| 2 | B (A) | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one | non-polymer | 493.0 | 1 | Chemie (59T) | |||
| 3 | C (A) | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A: 4 - 301 (UniProt: Q9Y6E0)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Ala 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34559.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 493.0 | |
| All* | Total formula weight | 35052.6 |
