7B2E
quadruple mutant of oxalyl-CoA decarboxylase from Methylorubrum extorquens with bound TPP and ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Putative oxalyl-CoA decarboxylase (Oxc, yfdU) | polymer | 583 | 61682.9 | 8 | UniProt (C5AX46) Pfam (PF02776) Pfam (PF00205) Pfam (PF02775) | Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) | |
| 2 | AA, DA, I, L, O... (G, H, A, B, C...) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 8 | Chemie (TPP) | |||
| 3 | BA, EA, J, M, P... (G, H, A, B, C...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 8 | Chemie (ADP) | |||
| 4 | CA, FA, K, N, Q... (G, H, A, B, C...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 5 | GA, HA, IA, JA, KA... (A, B, C, D, E...) | water | water | 18.0 | 1272 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 583 (UniProt: C5AX46)
| PDB | External Database | Details |
|---|---|---|
| Gly 135 | Glu 135 | engineered mutation |
| Cys 415 | Ala 415 | engineered mutation |
| Phe 497 | Tyr 497 | engineered mutation |
| Gly 568 | Ser 568 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 493462.9 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 7014.6 | |
| All* | Total formula weight | 500477.5 |
