7B1O

Crystal structure of the indoleamine 2,3-dioxygenase 1 (IDO1) in complex with compound 22

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Indoleamine 2,3-dioxygenase 1	polymer	410	46164.1	2	UniProt (P14902) Pfam (PF01231) In PDB	Homo sapiens (Human)	IDO-1,Indoleamine-pyrrole 2,3-dioxygenase
2	A, B	4-chloranyl-N-[(1R)-1-[(1S,5R)-3-quinolin-4-yloxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide	non-polymer		420.9	2	Chemie (SLW)
3		water	water		18.0	39	Chemie (HOH)

Sequence modifications

A, B: 11 - 403 (UniProt: P14902)

PDB	External Database	Details
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Ser 0	-	expression tag
Ser 1	-	expression tag
Gly 2	-	expression tag
Leu 3	-	expression tag
Val 4	-	expression tag
Pro 5	-	expression tag
Arg 6	-	expression tag
Gly 7	-	expression tag
Ser 8	-	expression tag
His 9	-	expression tag
Met 10	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	92328.1
Non-Polymers*	Number of molecules	2
	Total formula weight	841.9
All*	Total formula weight	93170.0

*Water molecules are not included.