7B1B

Cryo-EM of Aedes Aegypti Toll5A dimer bound to Spz1C

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Toll-like receptor	polymer	768	87675.8	2	UniProt (A0A6I8TEX2) Pfam (PF13855) In PDB	Aedes aegypti (yellow fever mosquito)
2	D, P	AAEL013433-PA	polymer	112	12941.0	2	UniProt (Q16J57) Pfam (PF16077) UniProt (by SIFTS) (A0A6I8TNM9) In PDB	Aedes aegypti (yellow fever mosquito)
3	C, E, G, I, K	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	5	In PDB GlyTouCan (G15407YE)
4	H, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, B: 28 - 789 (UniProt: A0A6I8TEX2)

PDB	External Database	Details
Glu 790	-	expression tag
Asn 791	-	expression tag
Leu 792	-	expression tag
Tyr 793	-	expression tag
Phe 794	-	expression tag
Gln 795	-	expression tag

D, P: 1 - 102 (UniProt: Q16J57)

PDB	External Database	Details
Thr 103	-	expression tag
Gly 104	-	expression tag
Trp 105	-	expression tag
Ser 106	-	expression tag
His 107	-	expression tag
Pro 108	-	expression tag
Gln 109	-	expression tag
Phe 110	-	expression tag
Glu 111	-	expression tag
Lys 112	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	201233.6
Branched	Number of molecules	7
	Total formula weight	3781.5
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	205678.8

*Water molecules are not included.