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7B0S

TRPC4 in complex with inhibitor GFB-8438

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily c member 4apolymer915105278.84UniProt (U3N7D8)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF08344)
Pfam (PF00520)
Danio rerio (Zebrafish)
2E, H, K, N
(A, B, C, D)
5-chloranyl-4-[3-oxidanylidene-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1~{H}-pyridazin-6-onenon-polymer386.84Chemie (S9Q)
3F, I, L, O
(A, B, C, D)
CALCIUM IONnon-polymer40.14Chemie (CA)
4G, J, M, P
(A, B, C, D)
(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoatenon-polymer368.44Chemie (44E)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight421115.1
Non-Polymers*Number of molecules12
Total formula weight3180.8
All*Total formula weight424295.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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