7B02
Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thioredoxin glutathione reductase | polymer | 598 | 65061.1 | 1 | UniProt (Q962Y6) Pfam (PF00462) Pfam (PF07992) Pfam (PF02852) UniProt (by SIFTS) (A0A3Q0KFL1) | Schistosoma mansoni (Blood fluke) | |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C, D, I, K (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 4 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | F (A) | 4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid | non-polymer | 204.2 | 1 | Chemie (SJN) | |||
| 6 | G (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | J (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 9 | L (A) | water | water | 18.0 | 669 | Chemie (HOH) |
Sequence modifications
A: 1 - 598 (UniProt: Q962Y6)
| PDB | External Database | Details |
|---|---|---|
| Cys 597 | Unk 597 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65061.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1589.9 | |
| All* | Total formula weight | 66651.0 |
