7AYN
Crystal structure of the lectin domain of the FimH variant Arg98Ala, in complex with Methyl 3-chloro-4-D-mannopyranosyloxy-3-biphenylcarboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Type 1 fimbrin D-mannose specific adhesin | polymer | 158 | 16830.7 | 4 | UniProt (P08191) Pfam (PF09160) | Escherichia coli K12 | Protein FimH |
| 2 | E, H, J, K (A, B, C, D) | methyl 3-[3-chloranyl-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-phenyl]benzoate | non-polymer | 424.8 | 4 | Chemie (SBQ) | |||
| 3 | F, G, I, L (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 956 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 158 (UniProt: P08191)
| PDB | External Database | Details |
|---|---|---|
| Ala 98 | Arg 119 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67322.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1947.6 | |
| All* | Total formula weight | 69270.4 |
