7ARG

Notum in complex with ARUK3002704

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Palmitoleoyl-protein carboxylesterase NOTUM	polymer	383	43567.1	1	UniProt (Q6P988) Pfam (PF03283)	Homo sapiens (Human)	hNOTUM
2	B (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3	C, D, E, F, J... (A)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4	G (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
5	H, I, L, M, N (A)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
6	O (A)	methyl 4-(2,3-dihydroindol-1-yl)-4-oxidanylidene-butanoate	non-polymer		233.3	1	Chemie (RW8)
7	P (A)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A: 81 - 451 (UniProt: Q6P988)

PDB	External Database	Details
Glu 78	-	expression tag
Thr 79	-	expression tag
Gly 80	-	expression tag
Ser 330	Cys 330	engineered mutation
Gly 452	-	expression tag
Thr 453	-	expression tag
Lys 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43567.1
Non-Polymers*	Number of molecules	14
	Total formula weight	1419.3
All*	Total formula weight	44986.5

*Water molecules are not included.