7APX

yeast THO-Sub2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	THO complex subunit 2,Tho2	polymer	1620	186067.1	1	UniProt (P53552) Pfam (PF16134) Pfam (PF11732) Pfam (PF11262)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Low dye-binding protein 5,THO complex subunit RLR1,Zinc-regulated gene 13 protein
2	B (B)	THO complex subunit HPR1	polymer	720	84544.0	1	UniProt (P17629) Pfam (PF11957)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Hyperrecombination protein 1
3	C (C)	THO complex subunit THP2	polymer	261	30340.3	1	UniProt (O13539) Pfam (PF09432)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
4	D (D)	THO complex subunit MFT1	polymer	392	45055.0	1	UniProt (P33441) Pfam (PF05615)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Mitochondrial fusion target protein 1
5	E (E)	Protein TEX1	polymer	380	42315.2	1	UniProt (P53851) Pfam (PF00400)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Trex component 1
6	F (F)	ATP-dependent RNA helicase SUB2	polymer	400	45521.0	1	UniProt (Q07478) Pfam (PF00271) Pfam (PF00270)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Suppressor of BRR1 protein 2

Sequence modifications

A: 1 - 3000 (UniProt: P53552)

PDB	External Database	Details
Gly -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

A: 3001 - 3019 (PDB: 7APX)
F: 48 - 446 (UniProt: Q07478)

PDB	External Database	Details
Gly 47	-	expression tag
Ser 50	Gly 50	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	433842.6
All*	Total formula weight	433842.6

*Water molecules are not included.