Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7AOI

Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A1)	bL28m	polymer	217	25444.4	1	UniProt (A0A3L6L6A9)	Trypanosoma brucei
2	B (A2)	uL29m	polymer	463	53072.2	1	UniProt (Q38EM7) Pfam (PF06984)	Trypanosoma brucei
3	C (A3)	uL30m	polymer	150	17508.6	1	UniProt (A0A3L6L456)	Trypanosoma brucei
4	D (A5)	bL32m	polymer	55	6931.3	1	UniProt (A0A3L6LD92)	Trypanosoma brucei
5	E (A8)	bL33m	polymer	142	17173.0	1	UniProt (A0A3L6L070)	Trypanosoma brucei
6	F (AA)	mt-LSU rRNA	polymer	758	242538.5	1		Trypanosoma brucei
7	G (AE)	Ribosomal protein L3 mitochondrial, putative	polymer	367	42538.8	1	UniProt (Q580R4) Pfam (PF00297)	Trypanosoma brucei
8	H (AF)	Ribosomal protein L4/L1 family	polymer	442	51178.3	1	UniProt (A0A3L6KTM7) Pfam (PF00573)	Trypanosoma brucei
9	I (AI)	RIBOSOMAL_L9 domain-containing protein	polymer	212	25387.2	1	UniProt (A0A3L6L8Y1) Pfam (PF01281)	Trypanosoma brucei
10	J (AK)	Ribosomal protein L11,uL11m	polymer	278	29590.2	1	UniProt (A0A3L6LEQ0) Pfam (PF03946) Pfam (PF00298)	Trypanosoma brucei
11	K (AN)	50S ribosomal protein L13	polymer	171	20327.5	1	UniProt (A0A3L6LAE5) Pfam (PF00572)	Trypanosoma brucei
12	L (AP)	Ribosomal_L18e/L15P domain-containing protein	polymer	354	41643.4	1	UniProt (A0A3L6L758) Pfam (PF00828)	Trypanosoma brucei
13	M (AR)	50S ribosomal protein L17	polymer	256	30480.9	1	UniProt (A0A3L6LAG5) Pfam (PF01196)	Trypanosoma brucei
14	N (AT)	bL19m	polymer	138	16154.4	1	UniProt (A0A3L6LD66)	Trypanosoma brucei
15	O (AU)	bL20m	polymer	196	22376.4	1	UniProt (A0A3L6KV21)	Trypanosoma brucei
16	P (AV)	Ribosomal protein L21	polymer	180	20182.4	1	UniProt (A0A3L6LA68) Pfam (PF00829)	Trypanosoma brucei
17	Q (AW)	Ribosomal protein L22p/L17e	polymer	277	31952.1	1	UniProt (A0A3L6L4Z4) Pfam (PF00237)	Trypanosoma brucei
18	R (AX)	Ribosomal protein L23	polymer	165	19685.5	1	UniProt (A0A3L6KW11)	Trypanosoma brucei
19	S (AY)	uL24m	polymer	340	39724.7	1	UniProt (C9ZK52)	Trypanosoma brucei
20	T (Ae)	mL41	polymer	116	13153.1	1	UniProt (A0A3L6KTI0)	Trypanosoma brucei
21	U (Af)	mL42	polymer	133	15185.2	1	UniProt (A0A3L6KXE9)	Trypanosoma brucei
22	V (Ag)	Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain containing protein	polymer	185	22110.8	1	UniProt (A0A3L6LCE5) Pfam (PF05047)	Trypanosoma brucei
23	W (Al)	mL49	polymer	182	20508.8	1	UniProt (A0A3L6L7H5)	Trypanosoma brucei
24	X (Ao)	mL52	polymer	133	14975.8	1	UniProt (A0A3L6KS48)	Trypanosoma brucei
25	Y (Ap)	mL53	polymer	288	33284.6	1	UniProt (A0A3L6L3K9)	Trypanosoma brucei
26	Z (At)	mL63	polymer	145	17103.6	1	UniProt (C9ZU82)	Trypanosoma brucei
27	AA (Av)	mL64,mL64	polymer	197	23722.2	1	UniProt (A0A3L6KTC7)	Trypanosoma brucei
28	BA (BA)	mL67	polymer	798	89788.0	1	UniProt (D0A5V6)	Trypanosoma brucei
29	CA (BB)	mL68,mL68,mL68	polymer	371	40602.1	1	UniProt (A0A3L6KX69)	Trypanosoma brucei
30	DA (BD)	mL70	polymer	417	47556.8	1	UniProt (A0A3L6L6S3)	Trypanosoma brucei
31	EA (BE)	mL71	polymer	438	49032.2	1	UniProt (C9ZSQ8)	Trypanosoma brucei
32	FA (BF)	Tetratricopeptide repeat	polymer	421	48742.3	1	UniProt (A0A3L6LA84)	Trypanosoma brucei
33	GA (BH)	mL74	polymer	225	25893.4	1	UniProt (A0A3L6KXN2)	Trypanosoma brucei
34	HA (BI)	Mitochondrial RNA binding complex 1 subunit	polymer	323	37503.8	1	UniProt (A0A3L6KZH2)	Trypanosoma brucei
35	IA (BJ)	mL76	polymer	161	18931.5	1	UniProt (A0A3L6KX00)	Trypanosoma brucei
36	JA (BK)	Chaperone protein DNAj, putative,mL77,Chaperone protein DNAj, putative	polymer	273	30694.7	1	UniProt (C9ZQR6) Pfam (PF00226)	Trypanosoma brucei
37	KA (BL)	mL78	polymer	276	31316.1	1	UniProt (A0A3L6L166)	Trypanosoma brucei
38	LA (BN)	mL80	polymer	214	25435.6	1	UniProt (C9ZQF0)	Trypanosoma brucei
39	MA (BO)	mL81	polymer	227	25450.9	1	UniProt (A0A3L6KS29)	Trypanosoma brucei
40	NA (BQ)	Peptidyl-prolyl cis-trans isomerase	polymer	185	20286.8	1	UniProt (Q57WF8) Pfam (PF00160)	Trypanosoma brucei	PPIase
41	OA (BR)	mL84	polymer	195	23420.0	1	UniProt (A0A3L6L538)	Trypanosoma brucei
42	PA (BS)	mL85	polymer	144	16955.4	1	UniProt (Q38FG8)	Trypanosoma brucei
43	QA (BT)	mL86	polymer	167	19667.1	1	UniProt (A0A3L6L8W0)	Trypanosoma brucei
44	RA (BU)	mL87	polymer	82	9886.4	1	UniProt (A0A3L6KX50)	Trypanosoma brucei
45	SA (BW)	mL89	polymer	187	22082.2	1	UniProt (Q57WW5)	Trypanosoma brucei
46	TA (BX)	LIM domain containing protein,mL90	polymer	116	13189.0	1	UniProt (A0A3L6L637) Pfam (PF00412)	Trypanosoma brucei
47	UA (BZ)	Peptidyl-prolyl cis-trans isomerase	polymer	189	20411.1	1	UniProt (A0A3L6KTB1) Pfam (PF00160)	Trypanosoma brucei	PPIase
48	VA (Ba)	mL93	polymer	135	16882.2	1	UniProt (D0A4T0)	Trypanosoma brucei
49	WA (Bb)	mL94	polymer	103	11446.0	1	UniProt (A0A3L6L3K4)	Trypanosoma brucei
50	XA (Bc)	mL95	polymer	137	16813.2	1	UniProt (A0A3L6L276)	Trypanosoma brucei
51	YA (Bf)	mL98	polymer	86	10096.2	1	UniProt (A0A3L6L4A5)	Trypanosoma brucei
52	ZA (Bg)	mL99	polymer	82	9313.5	1	UniProt (A0A3L6LDF0)	Trypanosoma brucei
53	AB (Bh)	mL100,mL100	polymer	92	10554.3	1	UniProt (A0A3L6L2V1)	Trypanosoma brucei
54	BB (UA)	UNK1	polymer	46	3287.6	1		Trypanosoma brucei
55	CB (UB)	UNK2	polymer	9	657.7	1		Trypanosoma brucei
56	DB (UC)	UNK3	polymer	14	1013.1	1		Trypanosoma brucei
57	EB (UD)	UNK4	polymer	8	586.6	1		Trypanosoma brucei
58	FB (UE)	UNK5	polymer	12	870.9	1		Trypanosoma brucei
59	GB (UF)	UNK6/mt-LAF15_2	polymer	139	9897.8	1		Trypanosoma brucei
60	HB (UG)	UNK7	polymer	19	1368.5	1		Trypanosoma brucei
61	IB (UH)	UNK8	polymer	17	1226.3	1		Trypanosoma brucei
62	JB (UI)	UNK9	polymer	39	2790.1	1		Trypanosoma brucei
63	KB (UJ)	UNK10	polymer	25	1795.0	1		Trypanosoma brucei
64	LB (UK)	UNK11	polymer	47	3358.7	1		Trypanosoma brucei
65	MB (XA)	mt-LAF7,mt-LAF7	polymer	155	18502.1	1	UniProt (Q387S8)	Trypanosoma brucei
66	NB (XB)	DEAD-box helicase, putative,mt-LAF2	polymer	668	76345.5	1	UniProt (D0A9G9) Pfam (PF00270) Pfam (PF00271)	Trypanosoma brucei
67	OB (XC)	mt-LAF4	polymer	616	69432.4	1	UniProt (D0A7A5)	Trypanosoma brucei
68	PB, QB (XD, XE)	Acyl carrier protein	polymer	83	9779.9	2	UniProt (Q57WW9) Pfam (PF00550)	Trypanosoma brucei
69	RB (XF)	mt-LAF15_1	polymer	198	21686.5	1	UniProt (A0A3L6LB16)	Trypanosoma brucei
70	SB (XG)	50S ribosomal protein L14	polymer	170	19559.8	1	UniProt (A0A3L6LE16) Pfam (PF00238)	Trypanosoma brucei
71	TB (XH)	mt-LAF8	polymer	533	58945.9	1		Trypanosoma brucei
72	UB (XI)	mt-LAF14	polymer	703	78937.2	1	UniProt (Q57U79)	Trypanosoma brucei
73	VB (XJ)	RNA uridylyltransferase	polymer	150	17337.9	1	UniProt (A0A3L6L766) Pfam (PF02410)	Trypanosoma brucei
74	WB (XL)	GTP-binding protein, putative,mt-EngA	polymer	528	60253.1	1	UniProt (C9ZS56) Pfam (PF01926) Pfam (PF14714)	Trypanosoma brucei
75	XB (XM)	Complex1-LYR-like	polymer	91	10607.3	1	UniProt (A0A3L6L7X4)	Trypanosoma brucei
76	YB (XN)	mt-LAF12	polymer	620	70343.1	1	UniProt (Q57YY3)	Trypanosoma brucei
77	ZB (XO)	SpoU rRNA Methylase family	polymer	428	48530.0	1	UniProt (A0A3L6L241) Pfam (PF00588)	Trypanosoma brucei
78	AC (XP)	Pseudouridylate synthase, putative	polymer	371	42582.2	1	UniProt (Q38FJ3) Pfam (PF00849)	Trypanosoma brucei
79	BC (XQ)	GTP-binding protein	polymer	305	33914.9	1	UniProt (A0A3L6L0D5) Pfam (PF01926)	Trypanosoma brucei
80	CC (XR)	Lipase (Class 3)	polymer	161	18808.3	1	UniProt (A0A3L6L1Y4)	Trypanosoma brucei
81	DC (XS)	mL101	polymer	182	21799.3	1	UniProt (Q4GZ80)	Trypanosoma brucei
82	EC (XT)	mt-LAF19	polymer	97	11412.3	1	UniProt (A0A3L6KWY9)	Trypanosoma brucei
83	FC (A5)	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	1	Chemie (FES)
84	GC (Av)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
85	HC, IC, JC, KC (BX, Bh, XA)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
86	LC (XB)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
87	MC (XB)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
88	NC, OC (XL)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)

Sequence modifications

A3: 51 - 200 (UniProt: A0A3L6L456)

PDB	External Database	Details
Asp 198	Ala 198	variant

AK: 26 - 235 (UniProt: A0A3L6LEQ0)
AK: 239 - 306 (PDB: 7AOI)
AR: 11 - 266 (UniProt: A0A3L6LAG5)

PDB	External Database	Details
Trp 24	Tyr 24	variant

AX: 64 - 228 (UniProt: A0A3L6KW11)

PDB	External Database	Details
Tyr 126	His 126	variant

AY: 1 - 340 (UniProt: C9ZK52)

PDB	External Database	Details
Thr 6	Arg 6	variant

Av: 27 - 222 (UniProt: A0A3L6KTC7)

PDB	External Database	Details
Arg 163	Ile 163	variant

Av: 223 - 223 (PDB: 7AOI)
BB: 62 - 258 (UniProt: A0A3L6KX69)
BB: 264 - 341 (PDB: 7AOI)
BB: 346 - 450 (UniProt: A0A3L6KX69)
BI: 20 - 342 (UniProt: A0A3L6KZH2)

PDB	External Database	Details
Asn 227	Asp 227	variant

BJ: 173 - 333 (UniProt: A0A3L6KX00)

PDB	External Database	Details
Glu 329	Ala 329	conflict

BK: 84 - 233 (UniProt: C9ZQR6)
BK: 254 - 269 (PDB: 7AOI)
BK: 280 - 386 (UniProt: C9ZQR6)

PDB	External Database	Details
Thr 348	Leu 348	variant

BX: 61 - 174 (UniProt: A0A3L6L637)
BX: 175 - 176 (PDB: 7AOI)
Bh: 2 - 92 (UniProt: A0A3L6L2V1)
Bh: 93 - 93 (PDB: 7AOI)
XA: 3 - 156 (UniProt: Q387S8)
XA: 157 - 157 (PDB: 7AOI)
XB: 47 - 711 (UniProt: D0A9G9)

PDB	External Database	Details
Ala 301	Thr 301	conflict
Gly 462	Glu 463	conflict

XB: 712 - 713 (PDB: 7AOI)
XC: 1 - 616 (UniProt: D0A7A5)

PDB	External Database	Details
Pro 69	Ala 79	conflict

XL: 45 - 574 (UniProt: C9ZS56)
XL: 575 - 576 (PDB: 7AOI)
XO: 78 - 505 (UniProt: A0A3L6L241)

PDB	External Database	Details
Asp 337	Gly 337	conflict

XQ: 44 - 338 (UniProt: A0A3L6L0D5)

PDB	External Database	Details
Ala 331	Phe 331	conflict

XS: 22 - 203 (UniProt: Q4GZ80)

PDB	External Database	Details
Val 163	Leu 163	conflict

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	83
Polymers	Total formula weight	2331294.9
Non-Polymers*	Number of molecules	10
Non-Polymers*	Total formula weight	2598.7
All*	Total formula weight	2333893.6

*Water molecules are not included.

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)