Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7AOI

Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A1)	bL28m	polymer	217	25444.4	1	UniProt (A0A3L6L6A9)	Trypanosoma brucei
2	B (A2)	uL29m	polymer	463	53072.2	1	UniProt (Q38EM7) Pfam (PF06984)	Trypanosoma brucei
3	C (A3)	uL30m	polymer	150	17508.6	1	UniProt (A0A3L6L456)	Trypanosoma brucei
4	D (A5)	bL32m	polymer	55	6931.3	1	UniProt (A0A3L6LD92)	Trypanosoma brucei
5	E (A8)	bL33m	polymer	142	17173.0	1	UniProt (A0A3L6L070)	Trypanosoma brucei
6	F (AA)	mt-LSU rRNA	polymer	758	242538.5	1		Trypanosoma brucei
7	G (AE)	Ribosomal protein L3 mitochondrial, putative	polymer	367	42538.8	1	UniProt (Q580R4) Pfam (PF00297)	Trypanosoma brucei
8	H (AF)	Ribosomal protein L4/L1 family	polymer	442	51178.3	1	UniProt (A0A3L6KTM7)	Trypanosoma brucei
9	I (AI)	RIBOSOMAL_L9 domain-containing protein	polymer	212	25387.2	1	UniProt (A0A3L6L8Y1)	Trypanosoma brucei
10	J (AK)	Ribosomal protein L11,uL11m	polymer	278	29590.2	1	UniProt (A0A3L6LEQ0)	Trypanosoma brucei
11	K (AN)	50S ribosomal protein L13	polymer	171	20327.5	1	UniProt (A0A3L6LAE5)	Trypanosoma brucei
12	L (AP)	Ribosomal_L18e/L15P domain-containing protein	polymer	354	41643.4	1	UniProt (A0A3L6L758)	Trypanosoma brucei
13	M (AR)	50S ribosomal protein L17	polymer	256	30480.9	1	UniProt (A0A3L6LAG5)	Trypanosoma brucei
14	N (AT)	bL19m	polymer	138	16154.4	1	UniProt (A0A3L6LD66)	Trypanosoma brucei
15	O (AU)	bL20m	polymer	196	22376.4	1	UniProt (A0A3L6KV21)	Trypanosoma brucei
16	P (AV)	Ribosomal protein L21	polymer	180	20182.4	1	UniProt (A0A3L6LA68)	Trypanosoma brucei
17	Q (AW)	Ribosomal protein L22p/L17e	polymer	277	31952.1	1	UniProt (A0A3L6L4Z4)	Trypanosoma brucei
18	R (AX)	Ribosomal protein L23	polymer	165	19685.5	1	UniProt (A0A3L6KW11)	Trypanosoma brucei
19	S (AY)	uL24m	polymer	340	39724.7	1	UniProt (C9ZK52)	Trypanosoma brucei
20	T (Ae)	mL41	polymer	116	13153.1	1	UniProt (A0A3L6KTI0)	Trypanosoma brucei
21	U (Af)	mL42	polymer	133	15185.2	1	UniProt (A0A3L6KXE9)	Trypanosoma brucei
22	V (Ag)	Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain containing protein	polymer	185	22110.8	1	UniProt (A0A3L6LCE5)	Trypanosoma brucei
23	W (Al)	mL49	polymer	182	20508.8	1	UniProt (A0A3L6L7H5)	Trypanosoma brucei
24	X (Ao)	mL52	polymer	133	14975.8	1	UniProt (A0A3L6KS48)	Trypanosoma brucei
25	Y (Ap)	mL53	polymer	288	33284.6	1	UniProt (A0A3L6L3K9)	Trypanosoma brucei
26	Z (At)	mL63	polymer	145	17103.6	1	UniProt (C9ZU82)	Trypanosoma brucei
27	AA (Av)	mL64,mL64	polymer	197	23722.2	1	UniProt (A0A3L6KTC7)	Trypanosoma brucei
28	BA (BA)	mL67	polymer	798	89788.0	1	UniProt (D0A5V6)	Trypanosoma brucei
29	CA (BB)	mL68,mL68,mL68	polymer	371	40602.1	1	UniProt (A0A3L6KX69)	Trypanosoma brucei
30	DA (BD)	mL70	polymer	417	47556.8	1	UniProt (A0A3L6L6S3)	Trypanosoma brucei
31	EA (BE)	mL71	polymer	438	49032.2	1	UniProt (C9ZSQ8)	Trypanosoma brucei
32	FA (BF)	Tetratricopeptide repeat	polymer	421	48742.3	1	UniProt (A0A3L6LA84)	Trypanosoma brucei
33	GA (BH)	mL74	polymer	225	25893.4	1	UniProt (A0A3L6KXN2)	Trypanosoma brucei
34	HA (BI)	Mitochondrial RNA binding complex 1 subunit	polymer	323	37503.8	1	UniProt (A0A3L6KZH2)	Trypanosoma brucei
35	IA (BJ)	mL76	polymer	161	18931.5	1	UniProt (A0A3L6KX00)	Trypanosoma brucei
36	JA (BK)	Chaperone protein DNAj, putative,mL77,Chaperone protein DNAj, putative	polymer	273	30694.7	1	UniProt (C9ZQR6)	Trypanosoma brucei
37	KA (BL)	mL78	polymer	276	31316.1	1	UniProt (A0A3L6L166)	Trypanosoma brucei
38	LA (BN)	mL80	polymer	214	25435.6	1	UniProt (C9ZQF0)	Trypanosoma brucei
39	MA (BO)	mL81	polymer	227	25450.9	1	UniProt (A0A3L6KS29)	Trypanosoma brucei
40	NA (BQ)	Peptidyl-prolyl cis-trans isomerase	polymer	185	20286.8	1	UniProt (Q57WF8) Pfam (PF00160)	Trypanosoma brucei	PPIase
41	OA (BR)	mL84	polymer	195	23420.0	1	UniProt (A0A3L6L538)	Trypanosoma brucei
42	PA (BS)	mL85	polymer	144	16955.4	1	UniProt (Q38FG8)	Trypanosoma brucei
43	QA (BT)	mL86	polymer	167	19667.1	1	UniProt (A0A3L6L8W0)	Trypanosoma brucei
44	RA (BU)	mL87	polymer	82	9886.4	1	UniProt (A0A3L6KX50)	Trypanosoma brucei
45	SA (BW)	mL89	polymer	187	22082.2	1	UniProt (Q57WW5)	Trypanosoma brucei
46	TA (BX)	LIM domain containing protein,mL90	polymer	116	13189.0	1	UniProt (A0A3L6L637)	Trypanosoma brucei
47	UA (BZ)	Peptidyl-prolyl cis-trans isomerase	polymer	189	20411.1	1	UniProt (A0A3L6KTB1)	Trypanosoma brucei	PPIase
48	VA (Ba)	mL93	polymer	135	16882.2	1	UniProt (D0A4T0)	Trypanosoma brucei
49	WA (Bb)	mL94	polymer	103	11446.0	1	UniProt (A0A3L6L3K4)	Trypanosoma brucei
50	XA (Bc)	mL95	polymer	137	16813.2	1	UniProt (A0A3L6L276)	Trypanosoma brucei
51	YA (Bf)	mL98	polymer	86	10096.2	1	UniProt (A0A3L6L4A5)	Trypanosoma brucei
52	ZA (Bg)	mL99	polymer	82	9313.5	1	UniProt (A0A3L6LDF0)	Trypanosoma brucei
53	AB (Bh)	mL100,mL100	polymer	92	10554.3	1	UniProt (A0A3L6L2V1)	Trypanosoma brucei
54	BB (UA)	UNK1	polymer	46	3287.6	1		Trypanosoma brucei
55	CB (UB)	UNK2	polymer	9	657.7	1		Trypanosoma brucei
56	DB (UC)	UNK3	polymer	14	1013.1	1		Trypanosoma brucei
57	EB (UD)	UNK4	polymer	8	586.6	1		Trypanosoma brucei
58	FB (UE)	UNK5	polymer	12	870.9	1		Trypanosoma brucei
59	GB (UF)	UNK6/mt-LAF15_2	polymer	139	9897.8	1		Trypanosoma brucei
60	HB (UG)	UNK7	polymer	19	1368.5	1		Trypanosoma brucei
61	IB (UH)	UNK8	polymer	17	1226.3	1		Trypanosoma brucei
62	JB (UI)	UNK9	polymer	39	2790.1	1		Trypanosoma brucei
63	KB (UJ)	UNK10	polymer	25	1795.0	1		Trypanosoma brucei
64	LB (UK)	UNK11	polymer	47	3358.7	1		Trypanosoma brucei
65	MB (XA)	mt-LAF7,mt-LAF7	polymer	155	18502.1	1	UniProt (Q387S8)	Trypanosoma brucei
66	NB (XB)	DEAD-box helicase, putative,mt-LAF2	polymer	668	76345.5	1	UniProt (D0A9G9)	Trypanosoma brucei
67	OB (XC)	mt-LAF4	polymer	616	69432.4	1	UniProt (D0A7A5)	Trypanosoma brucei
68	PB, QB (XD, XE)	Acyl carrier protein	polymer	83	9779.9	2	UniProt (Q57WW9) Pfam (PF00550)	Trypanosoma brucei
69	RB (XF)	mt-LAF15_1	polymer	198	21686.5	1	UniProt (A0A3L6LB16)	Trypanosoma brucei
70	SB (XG)	50S ribosomal protein L14	polymer	170	19559.8	1	UniProt (A0A3L6LE16)	Trypanosoma brucei
71	TB (XH)	mt-LAF8	polymer	533	58945.9	1		Trypanosoma brucei
72	UB (XI)	mt-LAF14	polymer	703	78937.2	1	UniProt (Q57U79)	Trypanosoma brucei
73	VB (XJ)	RNA uridylyltransferase	polymer	150	17337.9	1	UniProt (A0A3L6L766)	Trypanosoma brucei
74	WB (XL)	GTP-binding protein, putative,mt-EngA	polymer	528	60253.1	1	UniProt (C9ZS56)	Trypanosoma brucei
75	XB (XM)	Complex1-LYR-like	polymer	91	10607.3	1	UniProt (A0A3L6L7X4)	Trypanosoma brucei
76	YB (XN)	mt-LAF12	polymer	620	70343.1	1	UniProt (Q57YY3)	Trypanosoma brucei
77	ZB (XO)	SpoU rRNA Methylase family	polymer	428	48530.0	1	UniProt (A0A3L6L241)	Trypanosoma brucei
78	AC (XP)	Pseudouridylate synthase, putative	polymer	371	42582.2	1	UniProt (Q38FJ3) Pfam (PF00849)	Trypanosoma brucei
79	BC (XQ)	GTP-binding protein	polymer	305	33914.9	1	UniProt (A0A3L6L0D5)	Trypanosoma brucei
80	CC (XR)	Lipase (Class 3)	polymer	161	18808.3	1	UniProt (A0A3L6L1Y4)	Trypanosoma brucei
81	DC (XS)	mL101	polymer	182	21799.3	1	UniProt (Q4GZ80)	Trypanosoma brucei
82	EC (XT)	mt-LAF19	polymer	97	11412.3	1	UniProt (A0A3L6KWY9)	Trypanosoma brucei
83	FC (A5)	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	1	Chemie (FES)
84	GC (Av)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
85	HC, IC, JC, KC (BX, Bh, XA)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
86	LC (XB)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
87	MC (XB)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
88	NC, OC (XL)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)

Sequence modifications

A3: 51 - 200 (UniProt: A0A3L6L456)

PDB	External Database	Details
Asp 198	Ala 198	variant

AK: 26 - 235 (UniProt: A0A3L6LEQ0)
AK: 239 - 306 (PDB: 7AOI)
AR: 11 - 266 (UniProt: A0A3L6LAG5)

PDB	External Database	Details
Trp 24	Tyr 24	variant

AX: 64 - 228 (UniProt: A0A3L6KW11)

PDB	External Database	Details
Tyr 126	His 126	variant

AY: 1 - 340 (UniProt: C9ZK52)

PDB	External Database	Details
Thr 6	Arg 6	variant

Av: 27 - 222 (UniProt: A0A3L6KTC7)

PDB	External Database	Details
Arg 163	Ile 163	variant

Av: 223 - 223 (PDB: 7AOI)
BB: 62 - 258 (UniProt: A0A3L6KX69)
BB: 264 - 341 (PDB: 7AOI)
BB: 346 - 450 (UniProt: A0A3L6KX69)
BI: 20 - 342 (UniProt: A0A3L6KZH2)

PDB	External Database	Details
Asn 227	Asp 227	variant

BJ: 173 - 333 (UniProt: A0A3L6KX00)

PDB	External Database	Details
Glu 329	Ala 329	conflict

BK: 84 - 233 (UniProt: C9ZQR6)
BK: 254 - 269 (PDB: 7AOI)
BK: 280 - 386 (UniProt: C9ZQR6)

PDB	External Database	Details
Thr 348	Leu 348	variant

BX: 61 - 174 (UniProt: A0A3L6L637)
BX: 175 - 176 (PDB: 7AOI)
Bh: 2 - 92 (UniProt: A0A3L6L2V1)
Bh: 93 - 93 (PDB: 7AOI)
XA: 3 - 156 (UniProt: Q387S8)
XA: 157 - 157 (PDB: 7AOI)
XB: 47 - 711 (UniProt: D0A9G9)

PDB	External Database	Details
Ala 301	Thr 301	conflict
Gly 462	Glu 463	conflict

XB: 712 - 713 (PDB: 7AOI)
XC: 1 - 616 (UniProt: D0A7A5)

PDB	External Database	Details
Pro 69	Ala 79	conflict

XL: 45 - 574 (UniProt: C9ZS56)
XL: 575 - 576 (PDB: 7AOI)
XO: 78 - 505 (UniProt: A0A3L6L241)

PDB	External Database	Details
Asp 337	Gly 337	conflict

XQ: 44 - 338 (UniProt: A0A3L6L0D5)

PDB	External Database	Details
Ala 331	Phe 331	conflict

XS: 22 - 203 (UniProt: Q4GZ80)

PDB	External Database	Details
Val 163	Leu 163	conflict

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	83
Polymers	Total formula weight	2331294.9
Non-Polymers*	Number of molecules	10
Non-Polymers*	Total formula weight	2598.7
All*	Total formula weight	2333893.6

*Water molecules are not included.

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)