7AO3
Crystal structure of CotB2 variant F149L in complex with alendronate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cyclooctat-9-en-7-ol synthase | polymer | 318 | 36736.5 | 2 | UniProt (C9K1X5) Pfam (PF19086) In PDB | Streptomyces melanosporofaciens | |
2 | A, B | 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE | non-polymer | 245.1 | 2 | Chemie (AHD) | |||
3 | A, B | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 4 | Chemie (MPD) | |||
4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | water | water | 18.0 | 468 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 307 (UniProt: C9K1X5)
PDB | External Database | Details |
---|---|---|
Leu 149 | Phe 149 | engineered mutation |
Ala 308 | - | expression tag |
Ala 309 | - | expression tag |
Ala 310 | - | expression tag |
Leu 311 | - | expression tag |
Glu 312 | - | expression tag |
His 313 | - | expression tag |
His 314 | - | expression tag |
His 315 | - | expression tag |
His 316 | - | expression tag |
His 317 | - | expression tag |
His 318 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 73473.0 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1179.6 | |
All* | Total formula weight | 74652.6 |