7AMH
SmBRD3(2), Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM-A-33, an iBET726 analogue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Putative bromodomain-containing protein 3, brd3 | polymer | 129 | 15029.9 | 2 | UniProt (A0A5K4EQL3) Pfam (PF00439) UniProt (by SIFTS) (A0A5K4ESD7) In PDB | Schistosoma mansoni (Blood fluke) | |
| 2 | A, B | 4-{(2S, 4R)-1-acetyl-4-[(1-benzothiophen-6-yl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl}benzoic acid | non-polymer | 456.6 | 2 | Chemie (RN5) | |||
| 3 | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 129 (UniProt: A0A5K4EQL3)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30059.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 913.1 | |
| All* | Total formula weight | 30973.0 |
