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7ALI

Crystal structure of the main protease (3CLpro/Mpro) of SARS-CoV-2 at 1.65A resolution (spacegroup P2(1)).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
3C-like proteinasepolymer30633825.52UniProt (P0DTD1)
Pfam (PF05409)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2C, D
(A, B)
waterwater18.0490Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67651.1
All*Total formula weight67651.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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