7AK3
CLK1 bound with CAF052
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dual specificity protein kinase CLK1 | polymer | 339 | 39581.5 | 1 | UniProt (P49759) Pfam (PF00069) In PDB | Homo sapiens (Human) | CDC-like kinase 1 |
2 | A | ~{N}-[3-fluoranyl-4-(4-methylpiperazin-1-yl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine | non-polymer | 404.4 | 1 | Chemie (RH8) | |||
3 | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 148 - 484 (UniProt: P49759)
PDB | External Database | Details |
---|---|---|
Ser 146 | - | expression tag |
Met 147 | - | expression tag |
Ala 432 | Arg 432 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39581.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 404.4 | |
All* | Total formula weight | 39986.0 |