7AIR

Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Solute carrier family 12 member 4	polymer	1074	119610.3	1	UniProt (Q9UP95) Pfam (PF00324) Pfam (PF03522)	Homo sapiens (Human)	Electroneutral potassium-chloride cotransporter 1,Erythroid K-Cl cotransporter 1,hKCC1
2	B (B)	Solute carrier family 12 member 4	polymer	1074	119690.3	1	UniProt (Q9UP95) Pfam (PF00324) Pfam (PF03522)	Homo sapiens (Human)	Electroneutral potassium-chloride cotransporter 1,Erythroid K-Cl cotransporter 1,hKCC1
3	C, D (C, D)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
4	E (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	F, H (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
6	G (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A: 20 - 1085 (UniProt: Q9UP95)

PDB	External Database	Details
Met 19	-	initiating methionine
Ala 1086	-	expression tag
Glu 1087	-	expression tag
Asn 1088	-	expression tag
Leu 1089	-	expression tag
Tyr 1090	-	expression tag
Phe 1091	-	expression tag
Gln 1092	-	expression tag

B: 20 - 1085 (UniProt: Q9UP95)

PDB	External Database	Details
Met 19	-	initiating methionine
Ala 1086	-	expression tag
Glu 1087	-	expression tag
Asn 1088	-	expression tag
Leu 1089	-	expression tag
Tyr 1090	-	expression tag
Phe 1091	-	expression tag
Gln 1092	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	239300.5
Branched	Number of molecules	3
	Total formula weight	1597.5
Non-Polymers*	Number of molecules	3
	Total formula weight	1235.6
All*	Total formula weight	242133.6

*Water molecules are not included.