7AFV
Crystal structure of tetrameric beta-2-microglobulin deltaN6 S52C stabilized by a covalent ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-2-microglobulin | polymer | 91 | 10766.1 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | C (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 3 | D, E (A, B) | 5-oxidanylidene-~{N}-(2-sulfanylethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide | non-polymer | 257.3 | 2 | Chemie (SJK) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 96 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 6 | - | initiating methionine |
| Cys 52 | Ser 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21532.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 636.8 | |
| All* | Total formula weight | 22168.9 |
