7AEJ

Crystal structure of asymmetric HIV-1 gp41 containing all membrane anchors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, A, B	Envelope glycoprotein gp160,Envelope glycoprotein gp160	polymer	192	21825.0	3	UniProt (B2CPZ5) Pfam (PF00517) UniProt (by SIFTS) (P04578) In PDB	Human immunodeficiency virus 1	Env polyprotein,Env polyprotein
2	D	2H10	polymer	122	13352.0	1		Lama glama

Sequence modifications

C, A, B: 512 - 620 (UniProt: B2CPZ5)

PDB	External Database	Details
Gly 501	-	expression tag
Ala 502	-	expression tag
Met 503	-	expression tag
Asp 504	-	expression tag
Tyr 505	-	expression tag
Lys 506	-	expression tag
Asp 507	-	expression tag
Asp 508	-	expression tag
Asp 509	-	expression tag
Asp 510	-	expression tag
Lys 511	-	expression tag
Leu 519	Phe 519	conflict

C, A, B: 629 - 718 (UniProt: B2CPZ5)

PDB	External Database	Details
Gly 621	-	linker
Ala 622	-	linker
Met 623	-	linker
Asp 624	-	linker
Asp 625	-	linker
Asp 626	-	linker
Asp 627	-	linker
Lys 628	-	linker
Arg 717	Phe 717	engineered mutation
Arg 718	Gln 718	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	78826.9
All*	Total formula weight	78826.9

*Water molecules are not included.