7AD1
Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(One up trimer)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein,Envelope glycoprotein,Spike glycoprotein,Envelope glycoprotein,SARS-CoV-2 S protein | polymer | 1297 | 142547.3 | 3 | UniProt (P0DTC2) UniProt (M1E1E4) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) Pfam (PF07921) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, F, G, H... (E, F, G, H, I...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
| 3 | N, O, P, Q, R... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
A, B, C: 1211 - 1238 (UniProt: M1E1E4)
A, B, C: 1242 - 1297 (PDB: 7AD1)
| PDB | External Database | Details |
|---|---|---|
| Asn 614 | Asp 614 | conflict |
| Ser 682 | Arg 682 | conflict |
| Gly 685 | Arg 685 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 942 | Ala 942 | conflict |
| Pro 987 | Val 987 | conflict |
| Gly 1209 | - | linker |
| Ser 1210 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Arg 1239 | - | linker |
| Ser 1240 | - | linker |
| Leu 1241 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 427642.0 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 4244.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2212.1 | |
| All* | Total formula weight | 434098.1 |
