7A9H

Truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Mycobacterium tuberculosis

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (AAA, BBB)	1-deoxy-D-xylulose-5-phosphate synthase,1-deoxy-D-xylulose-5-phosphate synthase	polymer	628	66690.5	2	UniProt (P9WNS3) Pfam (PF13292) Pfam (PF02779) Pfam (PF02780)	Mycobacterium tuberculosis H37Rv	1-deoxyxylulose-5-phosphate synthase,DXPS,1-deoxyxylulose-5-phosphate synthase,DXPS
2	C, E (AAA, BBB)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	D, F (AAA, BBB)	THIAMINE DIPHOSPHATE	non-polymer		425.3	2	Chemie (TPP)
4	G, H (AAA, BBB)	water	water		18.0	666	Chemie (HOH)

Sequence modifications

AAA, BBB: 29 - 217 (UniProt: P9WNS3)

PDB	External Database	Details
Met 1	-	initiating methionine
Lys 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Pro 9	-	expression tag
Met 10	-	expression tag
Ser 11	-	expression tag
Asp 12	-	expression tag
Tyr 13	-	expression tag
Asp 14	-	expression tag
Ile 15	-	expression tag
Pro 16	-	expression tag
Thr 17	-	expression tag
Thr 18	-	expression tag
Glu 19	-	expression tag
Asn 20	-	expression tag
Leu 21	-	expression tag
Tyr 22	-	expression tag
Phe 23	-	expression tag
Gln 24	-	expression tag
Gly 25	-	expression tag
Ala 26	-	expression tag
Met 27	-	expression tag
Gly 28	-	expression tag

AAA, BBB: 225 - 628 (UniProt: P9WNS3)

PDB	External Database	Details
Gly 218	-	linker
Gly 219	-	linker
Gly 220	-	linker
Gly 221	-	linker
Gly 222	-	linker
Gly 223	-	linker
Gly 224	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	133380.9
Non-Polymers*	Number of molecules	4
	Total formula weight	899.2
All*	Total formula weight	134280.2

*Water molecules are not included.