7A7G

Soluble epoxide hydrolase in complex with TK90

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bifunctional epoxide hydrolase 2	polymer	346	39648.5	2	UniProt (P34913) Pfam (PF00561)	Homo sapiens (Human)
2	C, D (A, B)	(2~{R})-2-[[4-[[4-methoxy-2-(trifluoromethyl)phenyl]methylcarbamoyl]phenyl]methyl]butanoic acid	non-polymer		409.4	2	Chemie (TK9)
3	E, F (A, B)	water	water		18.0	33	Chemie (HOH)

Sequence modifications

A, B: 222 - 555 (UniProt: P34913)

PDB	External Database	Details
Met 219	-	initiating methionine
Ala 220	-	expression tag
Ser 221	-	expression tag
Leu 556	-	expression tag
Leu 557	-	expression tag
Glu 558	-	expression tag
His 559	-	expression tag
His 560	-	expression tag
His 561	-	expression tag
His 562	-	expression tag
His 563	-	expression tag
His 564	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79297.1
Non-Polymers*	Number of molecules	2
	Total formula weight	818.8
All*	Total formula weight	80115.9

*Water molecules are not included.