7A6U

Cryo-EM structure of the cytoplasmic domain of human TRPC6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Short transient receptor potential channel 6	polymer	957	109784.7	4	UniProt (Q9Y210) Pfam (PF12796) Pfam (PF08344) Pfam (PF00520) Pfam (PF08016)	Homo sapiens (Human)	TrpC6,Transient receptor protein 6,TRP-6
2	E, F, G, H (A, B, C, D)	UNKNOWN ATOM OR ION	non-polymer		65.4	4	Chemie (UNX)

Sequence modifications

A, B, C, D: 1 - 931 (UniProt: Q9Y210)

PDB	External Database	Details
Ala 932	-	expression tag
Glu 933	-	expression tag
Asn 934	-	expression tag
Leu 935	-	expression tag
Tyr 936	-	expression tag
Phe 937	-	expression tag
Gln 938	-	expression tag
Ser 939	-	expression tag
His 940	-	expression tag
His 941	-	expression tag
His 942	-	expression tag
His 943	-	expression tag
His 944	-	expression tag
His 945	-	expression tag
His 946	-	expression tag
His 947	-	expression tag
His 948	-	expression tag
His 949	-	expression tag
Asp 950	-	expression tag
Tyr 951	-	expression tag
Lys 952	-	expression tag
Asp 953	-	expression tag
Asp 954	-	expression tag
Asp 955	-	expression tag
Asp 956	-	expression tag
Lys 957	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	439138.8
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	439400.4

*Water molecules are not included.