7A6T
Crystal Structure of Asn173Ser variant of Human Deoxyhypusine Synthase in complex with NAD and spermidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Deoxyhypusine synthase | polymer | 369 | 41017.5 | 2 | UniProt (P49366) Pfam (PF01916) | Homo sapiens (Human) | DHS |
| 2 | C, K (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, L (A, B) | SPERMIDINE | non-polymer | 145.2 | 2 | Chemie (SPD) | |||
| 4 | E, F, G, I, J... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | H (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 6 | M (B) | OXAMIC ACID | non-polymer | 89.0 | 1 | Chemie (OXM) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 369 (UniProt: P49366)
| PDB | External Database | Details |
|---|---|---|
| Ser 173 | Asn 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82035.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2156.9 | |
| All* | Total formula weight | 84191.9 |
