7A5Z
Structure of VIM-2 metallo-beta-lactamase with hydrolysed Faropenem imine product
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase VIM-2 | polymer | 242 | 25693.5 | 1 | UniProt (Q9K2N0) Pfam (PF00753) | Pseudomonas aeruginosa | Class B beta-lactamase,Class B carbapenemase VIM-2,Metallo beta lactamase VIM-2,Metallo beta-lactamase,Metallo-beta-lactamase VIM-2,Metallo-beta-lactamase vim-2,Mettalo-beta-lactamase VIM-2,VIM-2 metallo-beta-lactamase,VIM-2 protein |
| 2 | B (A) | (5~{Z})-2-[1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-5-(4-oxidanylbutylidene)-2~{H}-1,3-thiazole-4-carboxylic acid | non-polymer | 303.3 | 1 | Chemie (QZH) | |||
| 3 | C, D, E (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F, G (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | H (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | J (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 27 - 266 (UniProt: Q9K2N0)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25693.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 617.8 | |
| All* | Total formula weight | 26311.2 |
