Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7A5I

Structure of the human mitoribosome with A- P-and E-site mt-tRNAs

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(Y2)
nascent chainpolymer292486.11Homo sapiens
2B
(A3)
16S rRNApolymer1559500019.61GenBank (1025814679)Homo sapiens (Human)
3C
(B3)
mt-tRNAValpolymer7323266.91Homo sapiens
4D
(D3)
39S ribosomal protein L2, mitochondrialpolymer30533355.91UniProt (Q5T653)
Pfam (PF00181)
Pfam (PF03947)
Homo sapiens (Human)MRP-L2,Mitochondrial large ribosomal subunit protein uL2m
5E
(E3)
39S ribosomal protein L3, mitochondrialpolymer34838689.61UniProt (P09001)
Pfam (PF00297)
Homo sapiens (Human)MRP-L3,Mitochondrial large ribosomal subunit protein uL3m
6F
(F3)
39S ribosomal protein L4, mitochondrialpolymer31134970.21UniProt (Q9BYD3)
Pfam (PF00573)
Homo sapiens (Human)MRP-L4,Mitochondrial large ribosomal subunit protein uL4m
7G
(H3)
39S ribosomal protein L9, mitochondrialpolymer26730296.41UniProt (Q9BYD2)
Pfam (PF01281)
Pfam (PF22078)
Homo sapiens (Human)MRP-L9,Mitochondrial large ribosomal subunit protein bL9m
8H
(I3)
39S ribosomal protein L10, mitochondrialpolymer26129322.51UniProt (Q7Z7H8)
Pfam (PF00466)
Homo sapiens (Human)MRP-L10,39S ribosomal protein L8,mitochondrial,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m
9I
(J3)
39S ribosomal protein L11, mitochondrialpolymer19220716.21UniProt (Q9Y3B7)
Pfam (PF03946)
Pfam (PF00298)
Homo sapiens (Human)MRP-L11,Mitochondrial large ribosomal subunit protein uL11m
10J
(K3)
39S ribosomal protein L13, mitochondrialpolymer17820723.01UniProt (Q9BYD1)
Pfam (PF00572)
Homo sapiens (Human)MRP-L13,Mitochondrial large ribosomal subunit protein uL13m
11K
(L3)
39S ribosomal protein L14, mitochondrialpolymer14515973.71UniProt (Q6P1L8)
Pfam (PF00238)
Homo sapiens (Human)MRP-L14,39S ribosomal protein L32,mitochondrial,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m
12L
(M3)
39S ribosomal protein L15, mitochondrialpolymer29633473.81UniProt (Q9P015)
Pfam (PF00828)
Homo sapiens (Human)MRP-L15,Mitochondrial large ribosomal subunit protein uL15m
13M
(N3)
39S ribosomal protein L16, mitochondrialpolymer25128496.31UniProt (Q9NX20)
Pfam (PF00252)
Homo sapiens (Human)MRP-L16,Mitochondrial large ribosomal subunit protein uL16m
14N
(O3)
39S ribosomal protein L17, mitochondrialpolymer17520083.31UniProt (Q9NRX2)
Pfam (PF01196)
Homo sapiens (Human)MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m
15O
(P3)
Mitochondrial ribosomal protein L18, isoform CRA_bpolymer17920465.31UniProt (A8K9D2)
Pfam (PF00861)
Homo sapiens (Human)cDNA FLJ76688,highly similar to Homo sapiens HSPC071 mRNA
16P
(Q3)
39S ribosomal protein L19, mitochondrialpolymer29233585.01UniProt (P49406)
Pfam (PF01245)
Homo sapiens (Human)MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m
17Q
(R3)
39S ribosomal protein L20, mitochondrialpolymer14917479.71UniProt (Q9BYC9)
Pfam (PF00453)
Homo sapiens (Human)MRP-L20,Mitochondrial large ribosomal subunit protein bL20m
18R
(S3)
39S ribosomal protein L21, mitochondrialpolymer20522847.71UniProt (Q7Z2W9)
Pfam (PF00829)
Homo sapiens (Human)MRP-L21,Mitochondrial large ribosomal subunit protein bL21m
19S
(T3)
39S ribosomal protein L22, mitochondrialpolymer21224369.51UniProt (E7ESL0)
Pfam (PF00237)
Homo sapiens (Human)
20T
(U3)
39S ribosomal protein L23, mitochondrialpolymer15317807.21UniProt (Q16540)
Pfam (PF00276)
Homo sapiens (Human)MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like
21U
(V3)
39S ribosomal protein L24, mitochondrialpolymer21624953.91UniProt (Q96A35)
Pfam (PF00467)
Pfam (PF17136)
Homo sapiens (Human)MRP-L24,Mitochondrial large ribosomal subunit protein uL24m
22V
(W3)
39S ribosomal protein L27, mitochondrialpolymer14816102.91UniProt (Q9P0M9)
Pfam (PF01016)
Homo sapiens (Human)MRP-L27,Mitochondrial large ribosomal subunit protein bL27m
23W
(X3)
39S ribosomal protein L28, mitochondrialpolymer25630090.71UniProt (Q13084)
Pfam (PF00830)
Homo sapiens (Human)MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m
24X
(Y3)
39S ribosomal protein L47, mitochondrialpolymer25029508.51UniProt (Q9HD33)
Pfam (PF06984)
Homo sapiens (Human)MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1
25Y
(Z3)
39S ribosomal protein L30, mitochondrialpolymer16118582.81UniProt (Q8TCC3)
Pfam (PF00327)
Homo sapiens (Human)MRP-L30,39S ribosomal protein L28,mitochondrial,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m
26Z
(03)
39S ribosomal protein L32, mitochondrialpolymer18821437.81UniProt (Q9BYC8)
Pfam (PF01783)
Homo sapiens (Human)MRP-L32,Mitochondrial large ribosomal subunit protein bL32m
27AA
(13)
39S ribosomal protein L33, mitochondrialpolymer657635.21UniProt (O75394)
Pfam (PF00471)
Homo sapiens (Human)MRP-L33,Mitochondrial large ribosomal subunit protein bL33m
28BA
(23)
39S ribosomal protein L34, mitochondrialpolymer9210183.91UniProt (Q9BQ48)
Pfam (PF00468)
Homo sapiens (Human)MRP-L34,Mitochondrial large ribosomal subunit protein bL34m
29CA
(33)
39S ribosomal protein L35, mitochondrialpolymer18821558.51UniProt (Q9NZE8)
Pfam (PF01632)
Homo sapiens (Human)MRP-L35,Mitochondrial large ribosomal subunit protein bL35m
30DA
(43)
39S ribosomal protein L36, mitochondrialpolymer10311809.31UniProt (Q9P0J6)
Pfam (PF00444)
Homo sapiens (Human)MRP-L36,BRCA1-interacting protein 1,Mitochondrial large ribosomal subunit protein bL36m
31EA
(53)
39S ribosomal protein L37, mitochondrialpolymer42348183.31UniProt (Q9BZE1)
Pfam (PF07147)
Homo sapiens (Human)MRP-L37,39S ribosomal protein L2,mitochondrial,MRP-L2,Mitochondrial large ribosomal subunit protein mL37
32FA
(63)
39S ribosomal protein L38, mitochondrialpolymer38044659.41UniProt (Q96DV4)
Pfam (PF01161)
Homo sapiens (Human)MRP-L38,Mitochondrial large ribosomal subunit protein mL38
33GA
(73)
39S ribosomal protein L39, mitochondrialpolymer33838764.81UniProt (Q9NYK5)Homo sapiens (Human)MRP-L39,39S ribosomal protein L5,mitochondrial,MRP-L5,Mitochondrial large ribosomal subunit protein mL39
34HA
(83)
39S ribosomal protein L40, mitochondrialpolymer20624534.41UniProt (Q9NQ50)
Pfam (PF09812)
Homo sapiens (Human)MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis
35IA
(93)
39S ribosomal protein L41, mitochondrialpolymer13715404.71UniProt (Q8IXM3)
Pfam (PF09809)
Homo sapiens (Human)MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41
36JA
(a3)
39S ribosomal protein L42, mitochondrialpolymer14216691.21UniProt (Q9Y6G3)
Pfam (PF10210)
Homo sapiens (Human)MRP-L42,39S ribosomal protein L31,mitochondrial,MRP-L31,Mitochondrial large ribosomal subunit protein mL42
37KA
(b3)
39S ribosomal protein L43, mitochondrialpolymer15517452.81UniProt (Q8N983)
Pfam (PF05047)
Homo sapiens (Human)MRP-L43,Mitochondrial large ribosomal subunit protein mL43,Mitochondrial ribosomal protein bMRP36a
38LA
(c3)
39S ribosomal protein L44, mitochondrialpolymer33237583.31UniProt (Q9H9J2)
Pfam (PF22935)
Pfam (PF22892)
Homo sapiens (Human)MRP-L44,Mitochondrial large ribosomal subunit protein mL44
39MA
(d3)
39S ribosomal protein L45, mitochondrialpolymer30635402.91UniProt (Q9BRJ2)
Pfam (PF04280)
Homo sapiens (Human)MRP-L45,Mitochondrial large ribosomal subunit protein mL45
40NA
(e3)
39S ribosomal protein L46, mitochondrialpolymer27931748.11UniProt (Q9H2W6)
Pfam (PF11788)
Homo sapiens (Human)MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL
41OA
(f3)
39S ribosomal protein L48, mitochondrialpolymer19421856.21UniProt (Q96GC5)
Pfam (PF00338)
Homo sapiens (Human)MRP-L48,Mitochondrial large ribosomal subunit protein mL48
42PA
(g3)
39S ribosomal protein L49, mitochondrialpolymer16619225.01UniProt (Q13405)
Pfam (PF05046)
Homo sapiens (Human)MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1
43QA
(h3)
39S ribosomal protein L50, mitochondrialpolymer15818349.91UniProt (Q8N5N7)
Pfam (PF10501)
Homo sapiens (Human)MRP-L50,Mitochondrial large ribosomal subunit protein mL50
44RA
(i3)
39S ribosomal protein L51, mitochondrialpolymer12815125.91UniProt (Q4U2R6)
Pfam (PF10244)
Homo sapiens (Human)MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64
45SA
(j3)
cDNA FLJ76418, highly similar to Homo sapiens mitochondrial ribosomal protein L52 (MRPL52), transcript variant 1, mRNApolymer12313696.71UniProt (A8K7J6)
Pfam (PF18699)
Homo sapiens (Human)
46TA
(k3)
39S ribosomal protein L53, mitochondrialpolymer11212125.91UniProt (Q96EL3)
Pfam (PF10780)
Homo sapiens (Human)MRP-L53,Mitochondrial large ribosomal subunit protein mL53
47UA
(l3)
39S ribosomal protein L54, mitochondrialpolymer13815844.21UniProt (Q6P161)
Pfam (PF08561)
Homo sapiens (Human)MRP-L54,Mitochondrial large ribosomal subunit protein mL54
48VA
(m3)
39S ribosomal protein L55, mitochondrialpolymer12815160.41UniProt (Q7Z7F7)
Pfam (PF09776)
Homo sapiens (Human)MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55
49WA
(o3)
Ribosomal protein 63, mitochondrialpolymer10212292.31UniProt (Q9BQC6)
Pfam (PF14978)
Homo sapiens (Human)hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57
50XA
(p3)
Peptidyl-tRNA hydrolase ICT1, mitochondrialpolymer20623674.21UniProt (Q14197)
Pfam (PF00472)
Homo sapiens (Human)39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62
51YA
(q3)
Growth arrest and DNA damage-inducible proteins-interacting protein 1polymer22225426.91UniProt (Q8TAE8)
Pfam (PF10147)
Homo sapiens (Human)39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP-1,p53-responsive gene 6 protein
52ZA
(r3)
39S ribosomal protein S18a, mitochondrialpolymer19622224.11UniProt (Q9NVS2)
Pfam (PF01084)
Homo sapiens (Human)S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66
53AB
(s3)
39S ribosomal protein S30, mitochondrialpolymer43950429.61UniProt (Q9NP92)
Pfam (PF07147)
Homo sapiens (Human)S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9
54BB, CB
(t3, A5)
Unknown protein/protein extensionpolymer282401.02Homo sapiens
55DB
(B6)
28S ribosomal protein S2, mitochondrialpolymer29633298.21UniProt (Q9Y399)
Pfam (PF00318)
Homo sapiens (Human)S2mt,Mitochondrial small ribosomal subunit protein uS2m
56EB
(C6)
28S ribosomal protein S24, mitochondrialpolymer16719046.21UniProt (Q96EL2)
Pfam (PF14955)
Homo sapiens (Human)S24mt,Mitochondrial small ribosomal subunit protein uS3m,bMRP-47,bMRP47
57FB
(D6)
28S ribosomal protein S5, mitochondrialpolymer43048094.61UniProt (P82675)
Pfam (PF21251)
Pfam (PF00333)
Pfam (PF03719)
Homo sapiens (Human)S5mt,Mitochondrial small ribosomal subunit protein uS5m
58GB
(E6)
28S ribosomal protein S6, mitochondrialpolymer12514250.61UniProt (P82932)
Pfam (PF01250)
Homo sapiens (Human)S6mt,Mitochondrial small ribosomal subunit protein bS6m
59HB
(F6)
28S ribosomal protein S7, mitochondrialpolymer24228186.21UniProt (Q9Y2R9)
Pfam (PF00177)
Homo sapiens (Human)S7mt,Mitochondrial small ribosomal subunit protein uS7m,bMRP-27a,bMRP27a
60IB
(G6)
28S ribosomal protein S9, mitochondrialpolymer39645909.91UniProt (P82933)
Pfam (PF00380)
Homo sapiens (Human)S9mt,Mitochondrial small ribosomal subunit protein uS9m
61JB
(H6)
28S ribosomal protein S10, mitochondrialpolymer20123033.51UniProt (P82664)
Pfam (PF00338)
Homo sapiens (Human)S10mt,Mitochondrial small ribosomal subunit protein uS10m
62KB
(I6)
28S ribosomal protein S11, mitochondrialpolymer19420648.81UniProt (P82912)
Pfam (PF00411)
Homo sapiens (Human)S11mt,Cervical cancer proto-oncogene 2 protein,HCC-2,Mitochondrial small ribosomal subunit protein uS11m
63LB
(J6)
28S ribosomal protein S12, mitochondrialpolymer13815200.91UniProt (O15235)
Pfam (PF00164)
Homo sapiens (Human)S12mt,MT-RPS12,Mitochondrial small ribosomal subunit protein uS12m
64MB
(K6)
28S ribosomal protein S14, mitochondrialpolymer12815168.81UniProt (O60783)
Pfam (PF00253)
Homo sapiens (Human)S14mt,Mitochondrial small ribosomal subunit protein uS14m
65NB
(L6)
28S ribosomal protein S15, mitochondrialpolymer25729903.31UniProt (P82914)
Pfam (PF00312)
Homo sapiens (Human)S15mt,Mitochondrial small ribosomal subunit protein uS15m
66OB
(M6)
28S ribosomal protein S16, mitochondrialpolymer13715371.91UniProt (Q9Y3D3)
Pfam (PF00886)
Homo sapiens (Human)S16mt,Mitochondrial small ribosomal subunit protein bS16m
67PB
(N6)
28S ribosomal protein S17, mitochondrialpolymer13014526.11UniProt (Q9Y2R5)
Pfam (PF00366)
Homo sapiens (Human)S17mt,Mitochondrial small ribosomal subunit protein uS17m
68QB
(O6)
28S ribosomal protein S18b, mitochondrialpolymer25829440.61UniProt (Q9Y676)
Pfam (PF01084)
Homo sapiens (Human)S18mt-b,28S ribosomal protein S18-2,mitochondrial,MRP-S18-2,Mitochondrial small ribosomal subunit protein bS18b,Mitochondrial small ribosomal subunit protein mS40
69RB
(P6)
28S ribosomal protein S18c, mitochondrialpolymer14215876.81UniProt (Q9Y3D5)
Pfam (PF01084)
Homo sapiens (Human)S18mt-c,28S ribosomal protein S18-1,mitochondrial,MRP-S18-1,Mitochondrial small ribosomal subunit protein bS18c,Mitochondrial small ribosomal subunit protein bS18m
70SB
(Q6)
28S ribosomal protein S21, mitochondrialpolymer8710764.71UniProt (P82921)
Pfam (PF01165)
Homo sapiens (Human)S21mt,Mitochondrial small ribosomal subunit protein bS21m
71TB
(R6)
28S ribosomal protein S22, mitochondrialpolymer36041337.31UniProt (P82650)
Pfam (PF10245)
Homo sapiens (Human)S22mt,Mitochondrial small ribosomal subunit protein mS22
72UB
(S6)
28S ribosomal protein S23, mitochondrialpolymer19021805.71UniProt (Q9Y3D9)
Pfam (PF10484)
Homo sapiens (Human)S23mt,Mitochondrial small ribosomal subunit protein mS23
73VB
(T6)
28S ribosomal protein S25, mitochondrialpolymer17320146.41UniProt (P82663)
Pfam (PF05047)
Homo sapiens (Human)S25mt,Mitochondrial small ribosomal subunit protein mS25
74WB
(U6)
28S ribosomal protein S26, mitochondrialpolymer20524259.81UniProt (Q9BYN8)
Pfam (PF14943)
Homo sapiens (Human)S26mt,28S ribosomal protein S13,mitochondrial,S13mt,Mitochondrial small ribosomal subunit protein mS26
75XB
(V6)
28S ribosomal protein S27, mitochondrialpolymer41447669.31UniProt (Q92552)
Pfam (PF10037)
Homo sapiens (Human)S27mt,Mitochondrial ribosomal protein S27,Mitochondrial small ribosomal subunit protein mS27
76YB
(W6)
28S ribosomal protein S28, mitochondrialpolymer18720878.81UniProt (Q9Y2Q9)
Pfam (PF10246)
Homo sapiens (Human)S28mt,28S ribosomal protein S35,mitochondrial,S35mt,Mitochondrial small ribosomal subunit protein bS1m
77ZB
(X6)
28S ribosomal protein S29, mitochondrialpolymer39845634.41UniProt (P51398)
Pfam (PF10236)
Homo sapiens (Human)S29mt,Death-associated protein 3,DAP-3,Ionizing radiation resistance conferring protein,Mitochondrial small ribosomal subunit protein mS29
78AC
(Y6)
28S ribosomal protein S31, mitochondrialpolymer39545391.51UniProt (Q92665)
Pfam (PF15433)
Homo sapiens (Human)S31mt,Imogen 38,Mitochondrial small ribosomal subunit protein mS31
79BC
(Z6)
28S ribosomal protein S33, mitochondrialpolymer10612657.81UniProt (Q9Y291)
Pfam (PF08293)
Homo sapiens (Human)S33mt,Mitochondrial small ribosomal subunit protein mS33
80CC
(a6)
28S ribosomal protein S34, mitochondrialpolymer21825695.51UniProt (P82930)
Pfam (PF16053)
Homo sapiens (Human)S34mt,Mitochondrial small ribosomal subunit protein mS34
81DC
(b6)
28S ribosomal protein S35, mitochondrialpolymer32336898.31UniProt (P82673)
Pfam (PF10213)
Homo sapiens (Human)S35mt,28S ribosomal protein S28,mitochondrial,S28mt,Mitochondrial small ribosomal subunit protein mS35
82EC
(c6)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1polymer11813498.81UniProt (Q96BP2)
Pfam (PF06747)
Homo sapiens (Human)28S ribosomal protein S37,mitochondrial,MRP-S37,Mitochondrial small ribosomal subunit protein mS37,Nuclear protein C2360
83FC
(d6)
Aurora kinase A-interacting proteinpolymer19922395.31UniProt (Q9NWT8)
Pfam (PF08213)
Homo sapiens (Human)AURKA-interacting protein,28S ribosomal protein S38,mitochondrial,MRP-S38,Mitochondrial small ribosomal subunit protein mS38
84GC
(e6)
Pentatricopeptide repeat domain-containing protein 3, mitochondrialpolymer68978648.51UniProt (Q96EY7)
Pfam (PF22330)
Pfam (PF13812)
Homo sapiens (Human)28S ribosomal protein S39,mitochondrial,MRP-S39,Mitochondrial small ribosomal subunit protein mS39,Transformation-related gene 15 protein,TRG-15
85HC
(A6)
12S rRNApolymer954306135.21Homo sapiens
86IC
(i4)
mRNApolymer92903.81Homo sapiens
87JC, KC, LC
(99, 94, X)
mt-tRNApolymer7323379.03Homo sapiens
88AD, AE, AF, AG, AH...
(A3, A6, D3, g3, o3...)
MAGNESIUM IONnon-polymer24.3127Chemie (MG)
89FG, GG, JG, LG, NG...
(03, 43, r3, B6, O6...)
ZINC IONnon-polymer65.47Chemie (ZN)
90KG
(A5)
CHLORIDE IONnon-polymer35.51Chemie (CL)
91QG
(X6)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
Sequence modifications
A3: 1671 - 3229 (GenBank: 1025814679)
PDBExternal DatabaseDetails
U 3107Unk 3109conflict
X3: 1 - 256 (UniProt: Q13084)
PDBExternal DatabaseDetails
Ala 148Thr 148conflict
Ser 149Pro 149conflict
Gly 150Lys 150conflict
Q6: 1 - 87 (UniProt: P82921)
PDBExternal DatabaseDetails
Arg 50Cys 50conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains90
Total formula weight2955764.0
Non-Polymers*Number of molecules136
Total formula weight4023.3
All*Total formula weight2959787.2
*Water molecules are not included.

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon