7A41
MALT1 in complex with a NVS-MALT1 chemical probe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | polymer | 404 | 45679.4 | 2 | UniProt (Q9UDY8) Pfam (PF00656) Pfam (PF18703) In PDB | Homo sapiens (Human) | MALT lymphoma-associated translocation,Paracaspase |
| 2 | A, B | ~{N}-[(1~{S})-1-[4-[[2-chloranyl-7-[(1~{S})-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]amino]phenyl]-2,2,2-tris(fluoranyl)ethyl]-~{N}-methyl-1,1-bis(oxidanylidene)thiane-4-carboxamide | non-polymer | 574.0 | 2 | Chemie (QYQ) | |||
| 3 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A, B: 329 - 728 (UniProt: Q9UDY8)
| PDB | External Database | Details |
|---|---|---|
| Gly 325 | - | expression tag |
| Pro 326 | - | expression tag |
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91358.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1226.2 | |
| All* | Total formula weight | 92584.9 |
