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7A3E

Intertwined dimer of the c-Src SH3 domain mutant T126S

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proto-oncogene tyrosine-protein kinase Srcpolymer616792.31UniProt (P00523)
Pfam (PF00018)
Gallus gallus (Chicken)Proto-oncogene c-Src,pp60c-src,p60-Src
2B, C
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
3D
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
4E
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
5F
(A)
waterwater18.023Chemie (HOH)
Sequence modifications
A: 81 - 141 (UniProt: P00523)
PDBExternal DatabaseDetails
Ser 126Thr 126engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight6792.3
Non-Polymers*Number of molecules4
Total formula weight458.5
All*Total formula weight7250.8
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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