7A3A
Intertwined dimer of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 60 | 6723.3 | 1 | UniProt (P00523) Pfam (PF00018) | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | B (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 3 | C (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E, F (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | G (A) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A: 82 - 141 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Leu 111 | Val 111 | engineered mutation |
| Ser 113 | Asn 113 | engineered mutation |
| Ser 114 | Thr 114 | engineered mutation |
| Glu 128 | Gln 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6723.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 510.5 | |
| All* | Total formula weight | 7233.8 |
