7A34
Intertwined dimer of the c-Src SH3 domain mutant V111L-N113S-T114S
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Proto-oncogene tyrosine-protein kinase Src | polymer | 60 | 6722.3 | 1 | UniProt (P00523) Pfam (PF00018) In PDB | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
2 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
3 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
4 | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
A: 82 - 141 (UniProt: P00523)
PDB | External Database | Details |
---|---|---|
Leu 111 | Val 111 | engineered mutation |
Ser 113 | Asn 113 | engineered mutation |
Ser 114 | Thr 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 6722.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 362.4 | |
All* | Total formula weight | 7084.7 |