7A31
Crystal structure of the c-Src SH3 domain mutant S94A-T98D-V111L-N113S-T114S at pH 4.5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Proto-oncogene tyrosine-protein kinase Src | polymer | 60 | 6720.3 | 2 | UniProt (P00523) Pfam (PF00018) In PDB | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
2 | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A, B: 82 - 141 (UniProt: P00523)
PDB | External Database | Details |
---|---|---|
Ala 94 | Ser 94 | engineered mutation |
Asp 98 | Thr 98 | engineered mutation |
Leu 111 | Val 111 | engineered mutation |
Ser 113 | Asn 113 | engineered mutation |
Ser 114 | Thr 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13440.5 | |
All* | Total formula weight | 13440.5 |