7A2U
Crystal structure of the Fyn SH3 domain L112V-S114N-S115T at pH 4.5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein kinase Fyn | polymer | 60 | 6822.4 | 1 | UniProt (P06241) Pfam (PF00018) In PDB | Homo sapiens (Human) | Proto-oncogene Syn,Proto-oncogene c-Fyn,Src-like kinase,SLK,p59-Fyn |
2 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
3 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 83 - 142 (UniProt: P06241)
PDB | External Database | Details |
---|---|---|
Val 112 | Leu 112 | engineered mutation |
Asn 114 | Ser 114 | engineered mutation |
Thr 115 | Ser 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 6822.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 59.0 | |
All* | Total formula weight | 6881.4 |