7A2N
Crystal structure of the Fyn SH3 domain A95S-D99T mutant in space group P21
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tyrosine-protein kinase Fyn | polymer | 60 | 6797.4 | 4 | UniProt (P06241) Pfam (PF00018) | Homo sapiens (Human) | Proto-oncogene Syn,Proto-oncogene c-Fyn,Src-like kinase,SLK,p59-Fyn |
| 2 | E, J, K, N, O... (A, B, C, D) | FORMIC ACID | non-polymer | 46.0 | 9 | Chemie (FMT) | |||
| 3 | F, G, H, I, L... (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 12 | Chemie (NA) | |||
| 4 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 83 - 142 (UniProt: P06241)
| PDB | External Database | Details |
|---|---|---|
| Ser 95 | Ala 95 | engineered mutation |
| Thr 99 | Asp 99 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 27189.4 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 690.1 | |
| All* | Total formula weight | 27879.5 |
