7A2L
Crystal structure of the Fyn SH3 domain mutant E129Q in space group C21 at pH 4.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein kinase Fyn | polymer | 60 | 6794.4 | 2 | UniProt (P06241) Pfam (PF00018) | Homo sapiens (Human) | Proto-oncogene Syn,Proto-oncogene c-Fyn,Src-like kinase,SLK,p59-Fyn |
| 2 | C, E (A) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 3 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A, B: 83 - 142 (UniProt: P06241)
| PDB | External Database | Details |
|---|---|---|
| Gln 129 | Glu 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13588.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 115.0 | |
| All* | Total formula weight | 13703.7 |
