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7A1O

FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 4-ethyl-2-oxoglutarate, AND CONSENSUS ANKYRIN REPEAT DOMAIN (20-MER)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hypoxia-inducible factor 1-alpha inhibitorpolymer34940328.31UniProt (Q9NWT6)
Pfam (PF13621)
Homo sapiens (Human)Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase
2B
(B)
CONSENSUS ANKYRIN REPEAT DOMAINpolymer202165.51synthetic construct
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D, E, F, H
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
5G
(A)
4-ethyl-2-oxoglutaratenon-polymer174.21Chemie (QVT)
6I, J
(A, B)
waterwater18.090Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42493.7
Non-Polymers*Number of molecules6
Total formula weight623.8
All*Total formula weight43117.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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