7A1G

Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	2	18S ribosomal RNA	polymer	1771	570585.3	1		Saccharomyces cerevisiae S288C
2	P	40S ribosomal protein S0-A	polymer	206	22811.1	1	UniProt (P32905) Pfam (PF00318) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Nucleic acid-binding protein NAB1A,Small ribosomal subunit protein uS2-A
3	Q	40S ribosomal protein S1-A	polymer	232	26314.7	1	UniProt (P33442) Pfam (PF01015) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP10A,Small ribosomal subunit protein eS1-A
4	R	40S ribosomal protein S2	polymer	216	23084.8	1	UniProt (P25443) Pfam (PF00333) Pfam (PF03719) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Omnipotent suppressor protein SUP44,RP12,S4,Small ribosomal subunit protein uS5,YS5
5	S	40S ribosomal protein S4-A	polymer	258	29167.9	1	UniProt (P0CX35) Pfam (PF08071) Pfam (PF01479) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP5,S7,Small ribosomal subunit protein eS4-A,YS6
6	T	40S ribosomal protein S6-A	polymer	228	26181.4	1	UniProt (P0CX37) Pfam (PF01092) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP9,S10,Small ribosomal subunit protein eS6-A,YS4
7	U	40S ribosomal protein S7-A	polymer	184	21000.5	1	UniProt (P26786) Pfam (PF01251) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP30,RP40,Small ribosomal subunit protein eS7-A
8	V	40S ribosomal protein S8-A	polymer	200	22537.8	1	UniProt (P0CX39) Pfam (PF01201) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP19,S14,Small ribosomal subunit protein eS8-A,YS9
9	W	40S ribosomal protein S9-A	polymer	184	21081.5	1	UniProt (O13516) Pfam (PF00163) Pfam (PF01479) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP21,S13,Small ribosomal subunit protein uS4-A,YP28,YS11
10	X	40S ribosomal protein S11-A	polymer	142	16272.1	1	UniProt (P0CX47) Pfam (PF16205) Pfam (PF00366) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP41,S18,Small ribosomal subunit protein uS17-A,YS12
11	Y	40S ribosomal protein S13	polymer	150	16928.7	1	UniProt (P05756) Pfam (PF08069) Pfam (PF00312) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	S27a,Small ribosomal subunit protein uS15,YS15
12	Z	40S ribosomal protein S14-B	polymer	127	13446.4	1	UniProt (P39516) Pfam (PF00411) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP59B,Small ribosomal subunit protein uS11-B
13	a	40S ribosomal protein S21-A	polymer	87	9758.8	1	UniProt (P0C0V8) Pfam (PF01249) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	S26,Small ribosomal subunit protein eS21-A,YS25
14	b	40S ribosomal protein S22-A	polymer	129	14518.9	1	UniProt (P0C0W1) Pfam (PF00410) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP50,S24,Small ribosomal subunit protein uS8-A,YP58,YS22
15	c	40S ribosomal protein S23-A	polymer	144	15942.7	1	UniProt (P0CX29) Pfam (PF00164) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP37,S28,Small ribosomal subunit protein uS12-A,YS14
16	d	40S ribosomal protein S24-A	polymer	134	15231.6	1	UniProt (P0CX31) Pfam (PF01282) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP50,Small ribosomal subunit protein eS24-A
17	e	40S ribosomal protein S26-B	polymer	97	11023.0	1	UniProt (P39939) Pfam (PF01283) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Small ribosomal subunit protein eS26-B
18	f	40S ribosomal protein S27-A	polymer	81	8762.2	1	UniProt (P35997) Pfam (PF01667) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP61,Small ribosomal subunit protein eS27-A,YS20
19	g	40S ribosomal protein S30-A	polymer	60	6779.1	1	UniProt (P0CX33) Pfam (PF04758) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Small ribosomal subunit protein eS30-A
20	E	40S ribosomal protein S15	polymer	117	13265.6	1	UniProt (Q01855) Pfam (PF00203) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RIG protein,RP52,S21,Small ribosomal subunit protein uS19,YS21
21	A	40S ribosomal protein S3	polymer	222	24631.7	1	UniProt (P05750) Pfam (PF07650) Pfam (PF00189) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP13,Small ribosomal subunit protein uS3,YS3
22	B	40S ribosomal protein S5	polymer	206	22908.3	1	UniProt (P26783) Pfam (PF00177) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP14,S2,Small ribosomal subunit protein uS7,YS8
23	C	40S ribosomal protein S10-A	polymer	92	11042.6	1	UniProt (Q08745) Pfam (PF03501) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Small ribosomal subunit protein eS10-A
24	D	40S ribosomal protein S12	polymer	121	13028.0	1	UniProt (P48589) Pfam (PF01248) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Small ribosomal subunit protein eS12
25	F	40S ribosomal protein S16-A	polymer	141	15659.2	1	UniProt (P0CX51) Pfam (PF00380) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP61R,Small ribosomal subunit protein uS9-A
26	H	40S ribosomal protein S17-B	polymer	125	14268.5	1	UniProt (P14127) Pfam (PF00833) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP51B,Small ribosomal subunit protein eS17-B
27	I	40S ribosomal protein S18-A	polymer	145	16940.4	1	UniProt (P0CX55) Pfam (PF00416) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Small ribosomal subunit protein uS13-A
28	J	40S ribosomal protein S19-A	polymer	143	15810.9	1	UniProt (P07280) Pfam (PF01090) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP55A,S16a,Small ribosomal subunit protein eS19-A,YP45,YS16A
29	K	40S ribosomal protein S20	polymer	100	11363.3	1	UniProt (P38701) Pfam (PF00338) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Small ribosomal subunit protein uS10
30	L	40S ribosomal protein S25-A	polymer	82	9540.3	1	UniProt (Q3E792) Pfam (PF03297) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	RP45,S31,Small ribosomal subunit protein eS25-A,YS23
31	M	40S ribosomal protein S29-A	polymer	53	6335.3	1	UniProt (P41057) Pfam (PF00253) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	S36,Small ribosomal subunit protein uS14-A,YS29
32	N	Ubiquitin-40S ribosomal protein S31	polymer	73	8388.0	1	UniProt (P05759) Pfam (PF01599) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
33	O	Guanine nucleotide-binding protein subunit beta-like protein	polymer	312	34151.5	1	UniProt (P38011) Pfam (PF00400) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Receptor for activated C kinase,Receptor of activated protein kinase C 1,RACK1,Small ribosomal subunit protein RACK1
34	h	40S ribosomal protein S28-A	polymer	63	7116.3	1	UniProt (Q3E7X9) Pfam (PF01200) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	S33,Small ribosomal subunit protein eS28-A,YS27
35	z, y	Eukaryotic translation initiation factor 3 subunit J	polymer	265	29611.2	2	UniProt (Q05775) Pfam (PF08597) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	eIF3j,Eukaryotic translation initiation factor 3 30 kDa subunit,eIF-3 30 kDa
36	x	Translation initiation factor RLI1	polymer	601	67714.5	1	UniProt (Q03195) Pfam (PF04068) Pfam (PF00037) Pfam (PF00005) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ATP-binding cassette sub-family E member RLI1,RNase L inhibitor
37	2, R, S, B, x	MAGNESIUM ION	non-polymer		24.3	80	Chemie (MG)
38	M, N	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
39	x	IRON/SULFUR CLUSTER	non-polymer		351.6	2	Chemie (SF4)
40	x	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)

Contents of the asymmetric unit

Polymers	Number of chains	37
	Total formula weight	1242815.7
Non-Polymers*	Number of molecules	85
	Total formula weight	3205.7
All*	Total formula weight	1246021.4

*Water molecules are not included.