7A16
CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR GSK2229238A (COMPOUND 43)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methionine aminopeptidase 2 | polymer | 371 | 41510.1 | 1 | UniProt (P50579) Pfam (PF00557) In PDB | Homo sapiens (Human) | MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67eIF2,Peptidase M |
2 | A | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
3 | A | 5,6-bis(fluoranyl)-3-(4-piperazin-1-yl-2-propan-2-yloxy-phenyl)-1~{H}-indole-2-carboxamide | non-polymer | 414.4 | 1 | Chemie (HZE) | |||
4 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
5 | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 41510.1 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1189.1 | |
All* | Total formula weight | 42699.3 |