7A14
CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR GSK2218325A (COMPOUND 32)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine aminopeptidase 2 | polymer | 371 | 41510.1 | 1 | UniProt (P50579) Pfam (PF00557) | Homo sapiens (Human) | MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67eIF2,Peptidase M |
| 2 | B, C, D, E, F... (A) | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
| 3 | I (A) | 5-chloranyl-6-fluoranyl-3-(2-propan-2-yloxyphenyl)-1~{H}-indole-2-carboxamide | non-polymer | 346.8 | 1 | Chemie (QVB) | |||
| 4 | J, K (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | L (A) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41510.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1121.5 | |
| All* | Total formula weight | 42631.6 |
