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7A13

CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR GSK1978537A (COMPOUND 27)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMethionine aminopeptidase 2polymer37141510.11UniProt (P50579)
Pfam (PF00557)
In PDB
Homo sapiens (Human)MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67eIF2,Peptidase M
2APHOSPHATE IONnon-polymer95.07Chemie (PO4)
3A5-chloranyl-3-(3-methoxyphenyl)-1~{H}-indole-2-carboxamidenon-polymer300.71Chemie (QW5)
4AMANGANESE (II) IONnon-polymer54.92Chemie (MN)
5waterwater18.0326Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41510.1
Non-Polymers*Number of molecules10
Total formula weight1075.4
All*Total formula weight42585.6
*Water molecules are not included.

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PDB entries from 2024-05-15

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