7A12
CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR GW557358X (COMPOUND 9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine aminopeptidase 2 | polymer | 371 | 41510.1 | 1 | UniProt (P50579) Pfam (PF00557) | Homo sapiens (Human) | MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67eIF2,Peptidase M |
| 2 | B, C, D, E, F... (A) | PHOSPHATE ION | non-polymer | 95.0 | 9 | Chemie (PO4) | |||
| 3 | K (A) | 5-chloranyl-3-phenyl-1~{H}-indole-2-carboxamide | non-polymer | 270.7 | 1 | Chemie (QVK) | |||
| 4 | L, M (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | N (A) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41510.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1235.3 | |
| All* | Total formula weight | 42745.5 |
