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7A0V

Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, ESynaptojanin-1polymer34939866.43UniProt (O43426)
In PDB
Homo sapiens (Human)Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1
2B, D, FNanobody 13015polymer13214559.93Lama glama
3A, EPHOSPHATE IONnon-polymer95.03Chemie (PO4)
4A, C, EMAGNESIUM IONnon-polymer24.33Chemie (MG)
5AGLYCEROLnon-polymer92.14Chemie (GOL)
6waterwater18.0359Chemie (HOH)
Sequence modifications
A, C, E: 528 - 873 (UniProt: O43426)
PDBExternal DatabaseDetails
Gly 525-expression tag
Ala 526-expression tag
Met 527-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight163278.9
Non-Polymers*Number of molecules10
Total formula weight726.2
All*Total formula weight164005.1
*Water molecules are not included.

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PDB entries from 2024-06-12

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