7A0V
Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Synaptojanin-1 | polymer | 349 | 39866.4 | 3 | UniProt (O43426) Pfam (PF22669) | Homo sapiens (Human) | Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1 |
| 2 | B, D, F (B, D, F) | Nanobody 13015 | polymer | 132 | 14559.9 | 3 | Lama glama | ||
| 3 | G, N, O (A, E) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 4 | H, M, P (A, C, E) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | I, J, K, L (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A, C, E: 528 - 873 (UniProt: O43426)
| PDB | External Database | Details |
|---|---|---|
| Gly 525 | - | expression tag |
| Ala 526 | - | expression tag |
| Met 527 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 163278.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 726.2 | |
| All* | Total formula weight | 164005.1 |
