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7A01

The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E1)
INTERNAL RIBOSOME ENTRY SITEpolymer15348550.51GenBank (JN000306.1)Halastavi arva RNA virus
2B
(e2)
28S RIBOSOMAL RNApolymer38251239030.91Oryctolagus cuniculus (Rabbit)
3C
(h2)
5.8S RIBOSOMAL RNApolymer15650143.61GenBank (4CXE_3)Oryctolagus cuniculus
4D
(d2)
5S RIBOSOMAL RNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus
5E
(p2)
Uncharacterized proteinpolymer698092.71UniProt (G1U001)
Pfam (PF01781)
Oryctolagus cuniculus (Rabbit)
6F
(k2)
eL14polymer13113972.41UniProt (G1T6D1)
Pfam (PF00238)
Oryctolagus cuniculus (Rabbit)
7G
(l2)
Ribosomal protein L24polymer637512.81UniProt (G1SE28)
Pfam (PF01246)
Oryctolagus cuniculus (Rabbit)
8H
(m2)
Uncharacterized proteinpolymer11913856.41UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)
Oryctolagus cuniculus (Rabbit)
9I
(o2)
Ribosomal protein L26polymer13415891.81UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)
Oryctolagus cuniculus (Rabbit)
10J
(q2)
uL15polymer14716489.41UniProt (G1SNY0)
Pfam (PF00828)
Oryctolagus cuniculus (Rabbit)
11K
(r2)
60S ribosomal protein L29polymer758706.31UniProt (G1TN82)
Pfam (PF01779)
UniProt (by SIFTS) (G1SGR6)
Oryctolagus cuniculus (Rabbit)
12L
(t2)
uL4polymer36241101.41UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)
Oryctolagus cuniculus (Rabbit)
13M
(u2)
eL31polymer10712635.71UniProt (G1SHG0)
Pfam (PF01198)
Oryctolagus cuniculus (Rabbit)
14N
(v2)
eL32polymer12815022.01UniProt (G1TUN8)
Pfam (PF01655)
Oryctolagus cuniculus (Rabbit)
15O
(w2)
60S RIBOSOMAL PROTEIN UL13polymer19923144.91UniProt (G5B8P1)
Pfam (PF00572)
Oryctolagus cuniculus
16P
(x2)
eL33polymer10912449.61UniProt (G1SF08)
Pfam (PF01247)
Oryctolagus cuniculus (Rabbit)
17Q
(y2)
eL34polymer11412994.61UniProt (G1U945)
Pfam (PF01199)
UniProt (by SIFTS) (G1TXG5)
Oryctolagus cuniculus (Rabbit)
18R
(92)
Uncharacterized proteinpolymer24426570.11UniProt (G1TT27)
Pfam (PF00181)
Pfam (PF03947)
Oryctolagus cuniculus (Rabbit)
19S
(A2)
uL29polymer12214435.41UniProt (G1SIT5)
Pfam (PF00831)
Oryctolagus cuniculus (Rabbit)
20T
(B2)
60S ribosomal protein L36polymer10211888.41UniProt (G1TTQ5)
Pfam (PF01158)
Oryctolagus cuniculus (Rabbit)
21U
(C2)
Ribosomal protein L37polymer8610090.91UniProt (U3KPD5)
Pfam (PF01907)
Oryctolagus cuniculus (Rabbit)
22V
(D2)
ribosomal protein eL39polymer506295.61UniProt (G1SYU7)
Pfam (PF00832)
Oryctolagus cuniculus (Rabbit)
23W
(E2)
60S RIBOSOMAL PROTEIN EL40polymer526199.61UniProt (P63048)
Pfam (PF01020)
Oryctolagus cuniculus
24X
(F2)
eL42polymer10412198.61UniProt (G1T040)
Pfam (PF00935)
Oryctolagus cuniculus (Rabbit)
25Y
(G2)
60S ribosomal protein L5polymer29234006.31UniProt (G1SYJ6)
UniProt (by SIFTS) (P19949)
Oryctolagus cuniculus (Rabbit)
26Z
(H2)
uL22polymer15317758.71UniProt (G1TVT6)
Pfam (PF00237)
UniProt (by SIFTS) (G1SCJ6)
Oryctolagus cuniculus (Rabbit)
27AA
(I2)
ribosomal protein eL43polymer9110168.21UniProt (G1SY53)
Pfam (PF01780)
Oryctolagus cuniculus (Rabbit)
28BA
(J2)
Uncharacterized proteinpolymer12514319.81UniProt (G1U7L1)
Pfam (PF01778)
Oryctolagus cuniculus (Rabbit)
29CA
(K2)
60S acidic ribosomal protein P0polymer19821747.31UniProt (G1SPK4)
Pfam (PF00466)
Pfam (PF17777)
Oryctolagus cuniculus (Rabbit)
30DA
(L2)
Ribosomal protein L10 (Predicted)polymer10211944.11UniProt (B7NZQ2)
Pfam (PF00252)
Oryctolagus cuniculus (Rabbit)
31EA
(M2)
Uncharacterized proteinpolymer16317689.51UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)
Oryctolagus cuniculus (Rabbit)
32FA
(R2)
Ribosomal_L6e_N domain-containing proteinpolymer354063.81UniProt (G1U1N5)
Pfam (PF03868)
Oryctolagus cuniculus (Rabbit)
33GA
(S2)
60S RIBOSOMAL PROTEIN EL18polymer18721556.51UniProt (Q07020)
Pfam (PF17135)
Oryctolagus cuniculus
34HA
(T2)
60S ribosomal protein L6polymer20122881.11UniProt (G1SKF7)
Pfam (PF01159)
Oryctolagus cuniculus (Rabbit)
35IA
(U2)
uL30polymer22526658.81UniProt (G1SV32)
Pfam (PF08079)
Pfam (PF00327)
Oryctolagus cuniculus (Rabbit)
36JA
(V2)
60S RIBOSOMAL PROTEIN EL8polymer24127452.51UniProt (P62424)
Pfam (PF01248)
Oryctolagus cuniculus
37KA
(W2)
Uncharacterized proteinpolymer19021627.21UniProt (G1SWI6)
Pfam (PF00347)
Oryctolagus cuniculus (Rabbit)
38LA
(X2)
Ribosomal protein L10 (Predicted)polymer10211682.71UniProt (B7NZQ2)
Pfam (PF00252)
Oryctolagus cuniculus (Rabbit)
39MA
(Y2)
Ribosomal protein L11polymer16919270.31UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)
Oryctolagus cuniculus (Rabbit)
40NA
(02)
Ribosomal protein L14polymer13816217.41UniProt (U3KNW6)
Pfam (PF01929)
UniProt (by SIFTS) (G1SZ12)
Oryctolagus cuniculus (Rabbit)
41OA
(12)
Ribosomal protein L15polymer20324076.11UniProt (G1T0C1)
Pfam (PF00827)
Oryctolagus cuniculus (Rabbit)
42PA
(22)
60S ribosomal protein L27polymer13515704.61UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)
Oryctolagus cuniculus (Rabbit)
43QA
(32)
60S RIBOSOMAL PROTEIN EL19polymer18021613.01UniProt (Q3T0W9)
Pfam (PF01280)
Oryctolagus cuniculus
44RA
(42)
Ribosomal proteinpolymer21724879.41UniProt (G1SKZ8)
Pfam (PF00687)
Oryctolagus cuniculus (Rabbit)
45SA
(52)
uL3polymer39445119.81UniProt (G1TL06)
Pfam (PF00297)
Oryctolagus cuniculus (Rabbit)
46TA
(62)
60S RIBOSOMAL PROTEIN EL20polymer17520677.31UniProt (Q3T003)
Pfam (PF01775)
Oryctolagus cuniculus
47UA
(72)
eL21polymer15918478.81UniProt (G1SHQ2)
Pfam (PF01157)
Oryctolagus cuniculus (Rabbit)
48VA
(82)
Ribosomal protein L22polymer9911481.21UniProt (G1TSG1)
Pfam (PF01776)
Oryctolagus cuniculus (Rabbit)
49WA
(K3)
18S RIBOSOMAL RNApolymer1801580908.91Oryctolagus cuniculus (Rabbit)
50XA
(s3)
40S RIBOSOMAL PROTEIN ES30polymer435011.01UniProt (P62866)
Pfam (PF04758)
Oryctolagus cuniculus
51YA
(13)
Ribosomal protein L30polymer9410498.31UniProt (G1TDL2)
Pfam (PF01248)
Oryctolagus cuniculus (Rabbit)
52ZA
(Q3)
40S ribosomal protein S27apolymer18821431.71UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
Oryctolagus cuniculus (Rabbit)Ubiquitin carboxyl extension protein 80,Ubiquitin-40S ribosomal protein S27a
53AB
(G3)
Ribosomal protein S11polymer15317786.01UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
Oryctolagus cuniculus (Rabbit)
54BB
(G5)
ribosomal protein uS13polymer13716170.81UniProt (G1TPG3)
Pfam (PF00416)
Oryctolagus cuniculus (Rabbit)
55CB
(a3)
ribosomal protein RACK1polymer31334669.11UniProt (G1SJB4)
Pfam (PF00400)
Oryctolagus cuniculus (Rabbit)
56DB
(a5)
Uncharacterized proteinpolymer13614544.71UniProt (G1T1F0)
Pfam (PF00411)
Oryctolagus cuniculus (Rabbit)
57EB
(A3)
ribosomal protein uS19polymer12715151.91UniProt (G1U0Q2)
Pfam (PF00203)
Oryctolagus cuniculus (Rabbit)
58FB
(T3)
Ribosomal protein S23polymer14115626.41UniProt (G1SZ47)
Pfam (PF00164)
Oryctolagus cuniculus (Rabbit)
59GB
(U3)
40S_SA_C domain-containing proteinpolymer20823390.81UniProt (G1TJH8)
Pfam (PF00318)
Oryctolagus cuniculus (Rabbit)
60HB
(V3)
40S ribosomal protein S3apolymer21324759.11UniProt (G1SS70)
Pfam (PF01015)
Oryctolagus cuniculus (Rabbit)
61IB
(W3)
S5 DRBM domain-containing proteinpolymer21824091.51Oryctolagus cuniculus (Rabbit)
62JB
(X3)
60s ribosomal protein l41polymer233213.11UniProt (A0A087WNH4)
Pfam (PF05162)
Oryctolagus cuniculus (Rabbit)
63KB
(Y3)
Ribosomal protein S3polymer22725158.51UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)
Oryctolagus cuniculus (Rabbit)
64LB
(j3)
40S ribosomal protein S4,40S ribosomal protein S4polymer26229527.71UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Oryctolagus cuniculus (Rabbit)
65MB
(J5)
Ribosomal protein S15apolymer12914734.41UniProt (G1TG89)
Pfam (PF00410)
Oryctolagus cuniculus (Rabbit)
66NB
(N3)
Ribosomal protein S5polymer19121525.91UniProt (U3KMN4)
Pfam (PF00177)
Oryctolagus cuniculus (Rabbit)
67OB
(b3)
40S ribosomal protein S6polymer23727471.51UniProt (G1TM55)
Pfam (PF01092)
Oryctolagus cuniculus (Rabbit)
68PB
(B3)
Uncharacterized proteinpolymer14115975.81UniProt (G1SGX4)
Pfam (PF00380)
Oryctolagus cuniculus (Rabbit)
69QB
(f3)
ribosomal protein eS28polymer647263.41UniProt (G1TIB4)
Pfam (PF01200)
Oryctolagus cuniculus (Rabbit)
70RB
(F3)
ribosomal protein uS15polymer15017128.21UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
Oryctolagus cuniculus (Rabbit)
71SB
(c3)
40S ribosomal protein S8polymer20624003.01UniProt (G1TJW1)
Pfam (PF01201)
Oryctolagus cuniculus (Rabbit)
72TB
(C3)
Uncharacterized proteinpolymer12914969.41UniProt (G1TU13)
Pfam (PF00833)
Oryctolagus cuniculus (Rabbit)
73UB
(d3)
Ribosomal protein S9 (Predicted)polymer18521649.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
Oryctolagus cuniculus (Rabbit)
74VB
(D3)
40S RIBOSOMAL PROTEIN ES21polymer839043.31UniProt (A0A1Z5KTU7)
Pfam (PF01249)
Oryctolagus cuniculus
75WB
(e3)
40S ribosomal protein S12polymer12413766.11UniProt (G1SFR8)
Pfam (PF01248)
Oryctolagus cuniculus (Rabbit)
76XB
(E3)
S10_plectin domain-containing proteinpolymer9811774.01UniProt (G1T168)
Pfam (PF03501)
Oryctolagus cuniculus (Rabbit)
77YB
(H3)
ribosomal protein uS14polymer536364.41UniProt (G1U7M4)
Pfam (PF00253)
Oryctolagus cuniculus (Rabbit)
78ZB
(H5)
Uncharacterized proteinpolymer14115812.31UniProt (G1TN62)
Pfam (PF01090)
Oryctolagus cuniculus (Rabbit)
79AC
(P3)
40S RIBOSOMAL PROTEIN ES7polymer18921603.21UniProt (A6H769)
Pfam (PF01251)
Oryctolagus cuniculus
80BC
(I3)
Ribosomal_S10 domain-containing proteinpolymer10411765.91UniProt (A0A5F9CX53)
Pfam (PF00338)
Oryctolagus cuniculus (Rabbit)
81CC
(I5)
40S ribosomal protein S24polymer12614604.31UniProt (A0A5F9CBF4)
Pfam (PF01282)
Oryctolagus cuniculus (Rabbit)
82DC
(L3)
40S ribosomal protein S27polymer839349.01UniProt (G1TZ76)
Pfam (PF01667)
Oryctolagus cuniculus (Rabbit)
83EC
(M3)
ribosomal protein eS25polymer758526.11UniProt (G1TDB3)
Pfam (PF03297)
Oryctolagus cuniculus (Rabbit)
84FC
(O3)
40S RIBOSOMAL PROTEIN ES26polymer9811184.21UniProt (Q56JV1)
Pfam (PF01283)
Oryctolagus cuniculus
85GC
(a7)
60S ribosomal protein L13polymer21024200.51UniProt (G1TPV0)Oryctolagus cuniculus (Rabbit)
86HC, IC, JC, KC, LC...
(C2, E2, F2, I2, H3...)
ZINC IONnon-polymer65.46Chemie (ZN)
Sequence modifications
w2: 5 - 203 (UniProt: G5B8P1)
PDBExternal DatabaseDetails
Leu 174Ile 170variant
Asp 194Glu 190variant
T2: 91 - 291 (UniProt: G1SKF7)
PDBExternal DatabaseDetails
Gln 224Lys 224variant
Lys 231Gln 231variant
82: 17 - 115 (UniProt: G1TSG1)
PDBExternal DatabaseDetails
Gly 32Arg 32variant
Ala 36Glu 36variant
Phe 39Ser 39variant
Gly 54Arg 54variant
Val 60Ala 60variant
Arg 97His 97variant
j3: 2 - 130 (UniProt: G1TK17)
j3: 131 - 263 (UniProt: G1TK17)
c3: 2 - 207 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47variant
D3: 1 - 83 (UniProt: A0A1Z5KTU7)
PDBExternal DatabaseDetails
Ser 3Asn 3variant
Asn 4Asp 4variant
Pro 33Gln 33variant
Ser 50Phe 50variant
His 76Asp 76variant
a7: 2 - 211 (UniProt: G1TPV0)
PDBExternal DatabaseDetails
Ala 47-insertion
Pro 48-insertion
Arg 49-insertion
Pro 50-insertion
Ala 51-insertion
Ala 52-insertion
Gly 53-insertion
Pro 54-insertion
Ile 55-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains85
Total formula weight3331693.9
Non-Polymers*Number of molecules6
Total formula weight392.5
All*Total formula weight3332086.4
*Water molecules are not included.

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PDB entries from 2024-10-30

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