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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6ZXF

Cryo-EM structure of a late human pre-40S ribosomal subunit - State G

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
12pre-18S ribosomal RNApolymer1874604431.91Homo sapiens (Human)
2A40S ribosomal protein SApolymer29532883.91UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Homo sapiens (Human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
3B40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
4C40S ribosomal protein S2polymer29331376.51UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (Human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
5E40S ribosomal protein S4, X isoformpolymer26329654.91UniProt (P62701)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Pfam (PF08071)
In PDB		Homo sapiens (Human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
6D40S ribosomal protein S3polymer24326729.41UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS3
7G40S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (Human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
8H40S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS7
9I40S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS8
10J40S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS4
11F40S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS7
12L40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS17
13K40S ribosomal protein S10polymer16518933.81UniProt (P46783)
Pfam (PF03501)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS10
14N40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS15
15O40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS11
16M40S ribosomal protein S12polymer13214539.01UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS12
17P40S ribosomal protein S15polymer14517076.21UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (Human)RIG protein,Small ribosomal subunit protein uS19
18R40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS17
19Q40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS9
20S40S ribosomal protein S18polymer15217759.81UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (Human)Ke-3,Ke3,Small ribosomal subunit protein uS13
21T40S ribosomal protein S19polymer14516091.61UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS19
22V40S ribosomal protein S21polymer839124.41UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS21
23W40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS8
24X40S ribosomal protein S23polymer14315844.71UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS12
25Y40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS24
26U40S ribosomal protein S20polymer11913398.81UniProt (P60866)
Pfam (PF00338)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS10
27Z40S ribosomal protein S25polymer12513776.21UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS25
28b40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (Human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
29c40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS28
30d40S ribosomal protein S29polymer566690.81UniProt (P62273)
Pfam (PF00253)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS14
31e40S ribosomal protein S30polymer596668.91UniProt (P62861)
Pfam (PF04758)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS30
32fUbiquitin-40S ribosomal protein S27apolymer15618004.01UniProt (P62979)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (Human)Ubiquitin carboxyl extension protein 80
33gReceptor of activated protein C kinase 1polymer31735115.71UniProt (P63244)
Pfam (PF00400)
In PDB		Homo sapiens (Human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
34jProbable RNA-binding protein EIF1ADpolymer16519081.11UniProt (Q8N9N8)
Pfam (PF01176)
In PDB		Homo sapiens (Human)Eukaryotic translation initiation factor 1A domain-containing protein,Haponin
35zSerine/threonine-protein kinase RIO1polymer56865692.11UniProt (Q9BRS2)
Pfam (PF01163)
In PDB		Homo sapiens (Human)RIO kinase 1
36yRNA-binding protein NOB1polymer41246742.91UniProt (Q9ULX3)
Pfam (PF17146)
Pfam (PF15017)
Pfam (PF08772)
In PDB		Homo sapiens (Human)Phosphorylation regulatory protein HP-10,Protein ART-4
37kLeucine-rich repeat-containing protein 47polymer58363563.91UniProt (Q8N1G4)
Pfam (PF13855)
Pfam (PF00560)
In PDB		Homo sapiens (Human)
38d, f, yZINC IONnon-polymer65.43Chemie (ZN)
39zMAGNESIUM IONnon-polymer24.32Chemie (MG)
40zADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
Sequence modifications
y: 1 - 412 (UniProt: Q9ULX3)
PDBExternal DatabaseDetails
Asn 10Asp 10conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains37
Total formula weight1405672.5
Non-Polymers*Number of molecules6
Total formula weight752.0
All*Total formula weight1406424.5
*Water molecules are not included.

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PDB entries from 2024-07-24

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