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6ZWP

p38a bound with SR348

Replaces:  6Y6W
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMitogen-activated protein kinase 14polymer36141395.21UniProt (Q16539)
Pfam (PF00069)
In PDB
Homo sapiens (Human)MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a
2A5-azanyl-~{N}-[[4-[[(2~{S})-4-cyclohexyl-1-[(4-fluorophenyl)amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamidenon-polymer596.71Chemie (OE8)
3waterwater18.097Chemie (HOH)
Sequence modifications
A: 1 - 360 (UniProt: Q16539)
PDBExternal DatabaseDetails
Gly 0-expression tag
His 48Leu 48conflict
Ala 263Thr 263conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41395.2
Non-Polymers*Number of molecules1
Total formula weight596.7
All*Total formula weight41991.9
*Water molecules are not included.

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PDB entries from 2024-05-01

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