6ZWE
Crystal structure of human acetylcholinesterase in complex with ((6-((2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl)triphenylphosphonium bromide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 542 | 59447.1 | 2 | UniProt (P22303) Pfam (PF00135) | Homo sapiens (Human) | AChE |
| 2 | C, E (C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 3 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G79924RM) | |||
| 4 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | G (A) | (2~{E},4~{E})-5-(1,3-benzodioxol-5-yl)-~{N}-[6-(triphenyl-$l^{5}-phosphanyl)hexyl]penta-2,4-dienamide | non-polymer | 563.7 | 1 | Chemie (QRH) | |||
| 6 | DA, EA, FA, GA, H... (B, A) | SULFATE ION | non-polymer | 96.1 | 18 | Chemie (SO4) | |||
| 7 | LA, R (B, A) | BROMIDE ION | non-polymer | 79.9 | 2 | Chemie (BR) | |||
| 8 | AA, BA, CA, MA, NA... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 23 | Chemie (CL) | |||
| 9 | YA, ZA (A, B) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 118894.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1565.5 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 3489.2 | |
| All* | Total formula weight | 123948.9 |
