6ZW2
Crystal structure of OXA-10loop48 in complex with hydrolyzed meropenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 244 | 27568.4 | 2 | UniProt (Q7BNC2) Pfam (PF00905) | Escherichia coli | |
| 2 | C, E, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 3 | D, M (A) | (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid | non-polymer | 401.5 | 2 | Chemie (8YL) | |||
| 4 | J (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | K, L, P, Q (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 537 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 263 (UniProt: Q7BNC2)
| PDB | External Database | Details |
|---|---|---|
| Tyr 208 | Phe 208 | conflict |
| - | Gly 210 | deletion |
| - | Val 211 | deletion |
| - | Gly 212 | deletion |
| Arg 211 | Glu 214 | conflict |
| Ile 212 | Ser 215 | conflict |
| Glu 213 | Asn 216 | conflict |
| Lys 215 | Gly 218 | conflict |
| Ile 216 | Val 219 | conflict |
| Gly 217 | Ala 220 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55136.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1537.4 | |
| All* | Total formula weight | 56674.2 |
