6ZUF
Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Histone chaperone ASF1A | polymer | 158 | 17928.0 | 2 | UniProt (Q9Y294) Pfam (PF04729) In PDB | Homo sapiens (Human) | Anti-silencing function protein 1 homolog A,hAsf1a,CCG1-interacting factor A,hCIA |
| 2 | C, D | C2 foldamer/peptide hybrid inhibitor of histone chaperone ASF1 | polymer | 9 | 1297.6 | 2 | Homo sapiens | ||
| 3 | A, B, C, D | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 4 | A, B, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 156 (UniProt: Q9Y294)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 38451.2 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1213.1 | |
| All* | Total formula weight | 39664.3 |
