6ZTC
CRYSTAL STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE IN COMPLEX WITH FRAGMENT 1A AT 1.84A RESOLUTION.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Hematopoietic prostaglandin D synthase | polymer | 200 | 23427.9 | 2 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) In PDB | Homo sapiens (Human) | H-PGDS,GST class-sigma,Glutathione S-transferase,Glutathione-dependent PGD synthase,Glutathione-requiring prostaglandin D synthase,Prostaglandin-H2 D-isomerase |
2 | A, B | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A, B | 1-[1-(3-fluorophenyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-5-yl]propan-1-one | non-polymer | 273.3 | 2 | Chemie (QPN) | |||
5 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
6 | water | water | 18.0 | 602 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 199 (UniProt: O60760)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 46855.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1461.8 | |
All* | Total formula weight | 48317.6 |