6ZRQ
two-protofilament amyloid structure of S20G variant of human amylin (IAPP - islet amyloid polypeptide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Islet amyloid polypeptide | polymer | 37 | 3878.3 | 12 | UniProt (P10997) Pfam (PF00214) | Homo sapiens | Amylin,Diabetes-associated peptide,DAP,Insulinoma amyloid peptide |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 37 (UniProt: P10997)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | Ser 53 | engineered mutation |
| Tyc 37 | Tyr 70 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 46539.5 | |
| All* | Total formula weight | 46539.5 |
