6ZRG
Crystal structure of OXA-10loop48 in complex with hydrolyzed doripenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Beta-lactamase | polymer | 244 | 27568.4 | 2 | UniProt (Q7BNC2) Pfam (PF00905) In PDB | Escherichia coli | |
| 2 | A | (4R,5S)-3-{[(3S,5S)-5-({[amino(dihydroxy)methyl]amino}methyl)pyrrolidin-3-yl]sulfanyl}-5-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 420.5 | 1 | Chemie (QP2) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 548 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 263 (UniProt: Q7BNC2)
| PDB | External Database | Details |
|---|---|---|
| Tyr 208 | Phe 208 | conflict |
| - | Gly 210 | deletion |
| - | Val 211 | deletion |
| - | Gly 212 | deletion |
| Arg 211 | Glu 214 | conflict |
| Ile 212 | Ser 215 | conflict |
| Glu 213 | Asn 216 | conflict |
| Lys 215 | Gly 218 | conflict |
| Ile 216 | Val 219 | conflict |
| Gly 217 | Ala 220 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55136.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1020.5 | |
| All* | Total formula weight | 56157.3 |
